Intraosseous acinic cell carcinoma

Abstract

Acinic cell carcinoma is an uncommon low-grade malignant tumor of salivary glands. It was first described by Nasse in 1892, arising in parotid salivary gland. Salivary gland tumors are also known to develop within jaw bones, arising within the jaw as a primary central lesion, and are extremely rare with only a few cases reported. We present a rare case report of 65-year-old woman with intraosseous acinic cell carcinoma of left side of the mandible.

Intraosseous clear cell mucoepidermoid carcinoma in the maxilla: A case report and review of literature

“…Although about 90% of CACC arose in the parotid gland, several cases of ACC in central jaw bone have been reported. 14,[17][18][19][20][21] CACC may be confused with well-differentiated intraosseous MEC. ACC has a polymorphous appearance and is characterized as proliferation of acinic-like cells containing serous components.…”

“…Although about 90% of CACC arose in the parotid gland, several cases of ACC in central jaw bone have been reported 14,17‐21 . CACC may be confused with well‐differentiated intraosseous MEC.…”

Acinic Cell Carcinoma of the Parotid Gland: A Case Report and Review of the Literature

“…They are composed of diverse cell types and include acinic cells, vacuolated cells, intercalated cells, nonspecific glandular cells and clear cells. Large lobules or nests of tumor cells with little intervening stroma are characteristics [ 9 , 10 , 11 ]. The histologic grading of acinic cell carcinomas is controversial, and unlike clinical staging, histomorphology has not proven to be reliable in predicting its behavior [ 12 ].…”