Intraoral Schwannomas: presentation of a series of 12 cases

Abstract

Introduction: Schwannomas are benign and not very frequent tumors of the peripheral nerves, derived from the nerve supporting Schwann cells. Study Design: Data were collected on the clinical manifestations (sex, age), location, size and symptonts of the lesions as well as the evolution time and the initial (presumption) diagnosis. Results: Twelve patients were documented, with a mean age of 29,5 ± 12,1 years (range 16-50) and a balanced gender distribution. The mean duration of the lesions was 42,17± 45,3 months. The lesion located in the floor of the mouth was the largest tumor, measuring about 4 cm in maximum diameter, while the average size of the 12 schwannomas was 2.04± 1.1 cm. Conclusion: We present 12 oral schwannomas diagnosed and treated over a period of 10 years. Key words:Schwannomas, oral benign tumor, neurilemmoma.

Oral peripheral nerve sheath tumors: A clinicopathological and immunohistochemical study of 32 cases in a Brazilian population

“…Areas covered by masticatory mucosa have been described as the most frequently affected by PNSTs, and most neurofibromas and PENs are found in such locations ( 6 , 9 ). Schwannomas are found in several locations, but are frequent in the lips ( 6 , 19 ), GCTs in the tongue ( 6 , 12 , 18 , 20 ) and traumatic neuromas in the tongue and lips ( 6 , 10 , 12 , 21 ).…”

Conflation of gingival overgrowth and schwannoma

“…Sanchis et al ,9 in a series of 12 cases of intraoral schwannoma, reported the initial diagnosis to be correct in only two cases while the other cases were tentatively diagnosed as fibroma, dermoid cyst, adenoma and even residual cyst. Although the clinical picture of the lesion at the time of presentation in our case differed from that shown classically by schwannoma, the history given by the patient of the presence of a nodule-like mass initially and gingival overgrowth might have masked the true character of the lesion which was revealed histopathologically.…”

Oral neural tumors: Clinicopathologic analysis of 157 cases and review of the literature

“…Head and neck is the most common site where SCH arise (30,31). In the oral cavity, however they are not as common as they represent 9.3% (30) – 13.5% (32) of all head and neck SCHs.…”

“…Most commonly, it presents as a peripheral lesion, but rarely it may arise inside the jawbones (10,33). Its most common sites of manifestation are the lips and specifically the lower lip (10,11,31) or the buccal mucosa (5,34). Clinically, oral SCHs manifest as slow-growing solitary masses covered by normal appearing mucosa that measure a few millimeters to many centimeters in diameter (31).…”