Intraoral minor salivary gland tumors: a retrospective study of 62 cases in a Venezuelan population

Abstract

From 1968 to 1992 sixty-two cases of tumors of minor salivary glands were diagnosed from a Venezuelan population at the Oral Histopathology Laboratory of the Central University of Venezuela School of Dentistry. The diagnosis of individual tumors was based on the 1991 World Health Organization classification. Tumors were analyzed considering histological type, age and sex of the patient, and intraoral location. Pleomorphic adenomas constituted the most common histological diagnosis of the benign sample (71%), and 62% of the malignant tumors were diagnosed as mucoepidermoid carcinomas. The principal location was the palate, and a marked female prevalence was observed. Geographic differences appear to exist when compared with results of studies representing a cross-section of different world population groups.

A clinicopathologic study of 196 intraoral minor salivary gland tumors

“…Intraoral MSGTs accounted for 0.28-1.9% of the specimens, as reported by other authors in USA, Japan, Venezuela and Thailand. 4, [9][10][11] In our series, malignant neoplasms constituted 46.3% of the cases which is in agreement with the results of the most previous studies. 5,9,12 However, some have shown a predominance of malignant tumors.…”

“…2-6,9-11,14,16 Figure 2 is similar to some reports, 14,15,17 but the authors in USA, Brazil, Venezuela, Australia, China and Ansari on 18 cases of MSGTs in central Iran, reported that MEC was the most frequent. 6,10,16,[18][19][20][21] According to these data, there is a geographic variation in relative frequency of Ad CC versus MEC. However, these two neoplasms are the first and second malignant tumors in the most series.…”

“…This ratio was reported from 1:1.02 15 to 1:2. 10 It has been suggested that gender distribution in SGTs is related to ethnic variations. 4,22 In conclusion, in the present population, PA was the most common neoplasm, the palate was the most commonly affected site, and female tendency of MSGTs was seen.…”

Perfil epidemiológico das neoplasias de glândulas salivares: análise de 245 casos

“…These findings are similar to other publications 12 , although they are different from studies reporting the mucoepidermoid carcinoma as the most frequent malignant neoplasia 2,14 . However, in the present study, two cases represent the difference between the number of cystic adenoid carcinoma and of mucoepidermoid, which is not considered significant when compared to other series.…”

“…Concerning head and neck regions, it is known that tumors of the salivary glands correspond, on average, to 3% of the affections on this site, the majority being of epithelial origin 1,2 . They present varied etiology and several risk factors have been identified so far, although lack of information from medical records and clinical files minimize the importance of these tumors in the tumorigenesis of salivary glands 3 .…”