Intraoperative Specimen Mammography for Margin Assessment in Breast-Conserving Surgery

Jin, Ming; Kim, Ji Young; Kim, Tae Hee; Kang, Doo Kyoung; Han, Se Hwan; Jung, Yongsik

doi:10.4048/jbc.2019.22.e58

Cited by 14 publications

(10 citation statements)

References 19 publications

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“…We did not provide any training to the pathologists and pathologists’ assistants in interpretation of Faxitron images. In addition to the uses we describe here, specimen mammography has been invoked for intraoperative margin assessment [ 9 , 10 ]. It is not known whether a pathologist with or without special training could make these assessments in a reliable manner.…”

Section: Discussionmentioning

confidence: 99%

In-laboratory breast specimen radiography reduces tissue block utilization and improves turnaround time of pathologic examination

2021

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Background This study was performed to determine whether in-laboratory specimen radiography reduces turnaround time or block utilization in surgical pathology. Methods Specimens processed during a 48-day trial of an in-lab cabinet radiography device (Faxitron) were compared to a control group of specimens imaged in the mammography suite during a prior 1-year period, and to a second group of specimens not undergoing imaging of any type. Results Cases imaged in the mammography suite had longer turnaround time than cases not requiring imaging (by 1.15 days for core biopsies, and 1.73 days for mastectomies; p < 0.0001). In contrast, cases imaged in-lab had turnaround time that was no longer than unimaged cases (p > 0.05 for core biopsies, lumpectomies and mastectomies). Mastectomies imaged in-lab required submission of fewer blocks than controls not undergoing any imaging (mean reduction of 10.6 blocks). Conclusions Availability of in-lab radiography resulted in clinically meaningful improvements in turnaround time and economically meaningful reductions in block utilization.

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Section: Discussionmentioning

confidence: 99%

In-laboratory breast specimen radiography reduces tissue block utilization and improves turnaround time of pathologic examination

2021

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“…To ensure negative margins, many techniques are suggested to assess the surgical margins. These include microscopic pathological studies, frozen section analysis, USG, and intraoperatively imprint cytology but with varying degrees of success [11,12]. In the current study, we evaluated the performance of specimen USG and the frozen sections as tools for assessing the margins.…”

Section: Discussionmentioning

confidence: 99%

“…Intra-operative ultrasound, imprint cytology, scrape cytology and specimen mammography have all been employed [11]. Various studies have compared the sensitivity of specimen imaging with the frozen techniques in assessment of margins [11,12]. In this study, specimen ultrasonography and frozen section were both used to assess tumor margins intra-operatively.…”

Section: Introductionmentioning

confidence: 99%

Intraoperative Specimen Ultrasonography: Is It a Reliable Tool for Margin Assessment Following Breast Conservation Surgery for Breast Carcinoma?

Kumar¹,

Tandon²,

Chintamani³

2021

Cureus

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Background: Assessment of margins after breast conservation surgery is an essential part of management in breast cancer and is important in prognostication of the patient. Various intra-operative techniques like frozen section and imprint cytology are in use to ensure negative margins but have their limitations in the fact that 3D evaluation is not feasible. These lead to false negatives and also are operator dependent. In order to obviate these shortcomings, various centers are using specimen imaging (specimen mammogram and ultrasonography).Aims and Objectives: 1) To evaluate the accuracy of specimen ultrasonography in assessing the margins following breast conservation surgery (BCS). 2) To compare the accuracy of intra-operative specimen ultrasonography with frozen section for assessment of excision margins following BCS.Materials and methods: Sixty-two biopsy-proven patients with breast cancer who underwent BCS were included in this prospective study at a tertiary cancer care center. The oriented specimens were evaluated by specimen ultrasonography and later by frozen section. The final histopathology served as the gold standard.Results: Specimen ultrasonography is found to be superior to frozen section in providing detailed assessment of margins in patients undergoing breast conservation. Specimen ultrasonography was also able to detect additional lesions which might be missed on frozen section, especially the in-situ carcinoma.

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“…Several studies demonstrated that intraoperative mammography reduced positive margins 3,4 . No significant difference was found between SR and frozen sectioning 5 . However, Kyle Ota reported a significant increase in false‐positive margins caused by SR 6 .…”

Section: Value 95% Confidence Intervalmentioning

confidence: 99%

The application of intraoperative specimen mammography for margin status assessment in breast‐conserving surgery: A single‐center retrospective study

Wang

Xü

et al. 2020

Breast J

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Intraoperative Specimen Mammography for Margin Assessment in Breast-Conserving Surgery

Cited by 14 publications

References 19 publications

In-laboratory breast specimen radiography reduces tissue block utilization and improves turnaround time of pathologic examination

In-laboratory breast specimen radiography reduces tissue block utilization and improves turnaround time of pathologic examination

Intraoperative Specimen Ultrasonography: Is It a Reliable Tool for Margin Assessment Following Breast Conservation Surgery for Breast Carcinoma?

The application of intraoperative specimen mammography for margin status assessment in breast‐conserving surgery: A single‐center retrospective study

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