Intraoperative Severe Anaphylaxis Due to Gelofusine During a Neurosurgical Procedure

Ghai, Babita; Wig, Jai Dev; Gupta, Vikas

doi:10.1213/01.ane.0000249002.62821.10

Cited by 7 publications

(3 citation statements)

References 6 publications

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“…[ 55 ] Previous hypersensitivity reaction to the same group of drug was observed in one case[ 26 ] and to the different group of drug was observed in two cases. [ 25 30 ] Grading of anaphylaxis cases were comparable for previous experience of allergic or drug reactions ( P = 0.2283; Chi-square test).…”

Section: Resultsmentioning

confidence: 92%

“…Out of 100 fully evaluated, 52 references were included in the analysis as per selection criteria. [ 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 ] The flow diagram for the article selection is presented as Figure 1 .…”

Section: Resultsmentioning

confidence: 99%

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Drug-induced anaphylactic reactions in Indian population: A systematic review

Patel¹,

Patel²,

Barvaliya³

et al. 2014

Indian Journal of Critical Care Medicine

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Background:Epidemiological data on drug-induced anaphylactic reactions are limited in India and are largely depending on studies from developed countries.Aim:The aim was to analyze the published studies of drug-induced anaphylaxis reported from India in relation with causative drugs and other clinical characteristics.Materials and Methods:The electronic databases were searched for Indian publications from 1998 to 2013 describing anaphylactic reactions. The information was collected for demographics, set up in which anaphylaxis occurred, causative drugs, incubation period, clinical features, associated allergic conditions, past reactions, co-morbid conditions, skin testing, IgE assays, therapeutic intervention and mortality. Reactions were analyzed for severity, causality, and preventability. Data were extracted and summarized by absolute numbers, mean (95% confidence interval [CI]), percentages and odds ratio (OR) (95% CI).Results:From 3839 retrieved references, 52 references describing 54 reactions were included. The mean age was 35.31 (95% CI: 30.52–40.10) years. Total female patients were 61.11%. Majority reactions were developed in perioperative conditions (53.70%), ward (20.37%) and home (11.11%). The major incriminated groups were antimicrobials (18.52%), nonsteroidal antiinflammatory drugs-(NSAIDs) (12.96%) and neuromuscular blockers (12.96%). Common causative drugs were diclofenac (11.11%), atracurium (7.41%) and β-lactams (5.96%). Cardiovascular (98.15%) and respiratory (81.48%) symptoms dominated the presentation. Skin tests and IgE assays were performed in 37.03% and 18.52% cases, respectively. The fatal cases were associated with complications (OR =5.04; 95% CI: 1.41–17.92), cerebral hypoxic damage (OR =6.80; 95% CI: 2.14–21.58) and preventable reactions (OR =14.33; 95% CI: 2.33–87.97).Conclusion:Antimicrobials, NSAIDs, and neuromuscular blockers are common causative groups. The most fatal cases can be prevented by avoiding allergen drugs.

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Section: Resultsmentioning

confidence: 92%

Section: Resultsmentioning

confidence: 99%

Drug-induced anaphylactic reactions in Indian population: A systematic review

Patel¹,

Patel²,

Barvaliya³

et al. 2014

Indian Journal of Critical Care Medicine

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“…Most anesthetic agents can cause vasodilatation, hypotension, and potential cardiopulmonary dysfunction. Several reports exist describing anaphylactic reaction to plasma expanders including Gelofusine, Haemaccel, and Dextran,[4] some of which resulted in fatalities. Dubrey et al .…”

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confidence: 99%

An unusual cause of anaphylaxis during surgery

Parikh

Shah

Singh

et al. 2013

Indian Journal of Critical Care Medicine

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Current awareness: Pharmacoepidemiology and drug safety

2007

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 20 sections: 1 Reviews; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Teratogens/fetal exposure; 20 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Intraoperative Severe Anaphylaxis Due to Gelofusine During a Neurosurgical Procedure

Cited by 7 publications

References 6 publications

Drug-induced anaphylactic reactions in Indian population: A systematic review

Drug-induced anaphylactic reactions in Indian population: A systematic review

An unusual cause of anaphylaxis during surgery

Current awareness: Pharmacoepidemiology and drug safety

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