Intraoperative Indocyanine Green Video-Angiography

Oh, Jae Keun; Shin, Hocheol; Kim, Tae Yup; Choi, Gwi Hyun; Ji, Gyu Yeul; Yi, Seong; Ha, Yoon; Kh, Kim; Yoon, Do Heum

doi:10.1097/brs.0b013e318213c41e

Cited by 26 publications

(6 citation statements)

References 9 publications

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“…Thus, the NIR fluorescence imaging may be suitable for intraoperative using, while it is not appropriate for screening of human body. Since a CCD camera and a microscope with an ICG filter, which enabled visualization of the invisible near-infrared light, have been previously used in surgery [11,12,[14][15][16], ICG-lactosome could function as a novel imaging probe, enabling the surgeon to easily diagnose the safety margin and small skip lesions intraoperatively.…”

Section: Discussionmentioning

confidence: 99%

“…Recently, there has been considerable focus on the potential use of indocyanine green (ICG) in intraoperative real-time imaging [10][11][12][13][14][15][16]. However, the strong binding of plasma proteins with ICG and its subsequent rapid clearance by the liver results in binding of ICG to the tumor only for a short duration after administration; thus, the use of ICG for tumor imaging applications is limited [17].…”

Section: Introductionmentioning

confidence: 99%

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Intraoperative Near-infrared Fluorescence Imaging with Novel Indocyanine Green-Loaded Nanocarrier for Spinal Metastasis: A Preliminary Animal Study

Funayama¹,

Sakane²,

Abe³

et al. 2012

TOBEJ

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Abstract:Marginal resection during resection of a spinal metastasis is frequently difficult because of the presence of important tissues such as the aorta, vena cava, and dura mater, including the spinal cord adjacent to the vertebral body. Thus, there is an urgent need for novel intraoperative imaging modalities with the ability to clearly identify bone metastasis. We have proposed a novel nanocarrier loaded with indocyanine green (ICG) (ICG-lactosome) with tumor selectivity attributable to its enhanced permeation and retention (EPR) effect. We studied its feasibility in intraoperative near-infrared (NIR) fluorescence diagnosis with ICG-lactosome for imaging spinal metastasis. A rat model of subcutaneous mammary tumor and a rat model of spinal metastasis of breast cancer were used. Fluorescence emitted by the subcutaneous tumors and the spinal metastasis were clearly detected for at least 24 h. Moreover, imaging of the dissected spine revealed clear fluorescence emitted by the metastatic lesion in the L6 vertebra while the normal bone lacked fluorescence. This study was the first report on NIR fluorescence imaging of spinal metastasis in vivo. NIR fluorescence imaging with ICG-lactosome could be an effective intraoperative imaging modality for detecting spinal metastasis.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Intraoperative Near-infrared Fluorescence Imaging with Novel Indocyanine Green-Loaded Nanocarrier for Spinal Metastasis: A Preliminary Animal Study

Funayama¹,

Sakane²,

Abe³

et al. 2012

TOBEJ

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“…It is given by intravenous route with a recommended dose of 0.2–0.5 mg/kg with a maximum daily dose of 5 mg/kg. [23] It bounds to proteins, mainly globulins, and remains intravascularly. The liver deals with its metabolism and excretion.…”

Section: Discussionmentioning

confidence: 99%

Review of avoidance of complications in cerebral aneurysm surgery: The Fujita experience

et al. 2019

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Avoidance of complications during cerebral aneurysm surgery marks the future outcome in the patient. Various modalities such as adequate opening of the Sylvian fissure, motor-evoked potential, endoscope-assisted microsurgery, indocyanine green dye, and dual image video angiography are available to reduce these complications during surgery, either by prevention of injury to the small perforators or the parent artery. We present our experience at the Fujita Health University Banbuntane Hospital, Japan, of the cerebral aneurysm surgery along with the use of these modalities in our patients from September 2014 to December 2016 along with a brief review of the various techniques for avoidance of complications.

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“…Additionally, there might be delay in the clearance of ICG from the venous shunt lesion. This may make understanding of arteriovenous shunts harder in AVM/AVF surgery where multiple ICG injections might be performed over the course of resection [27].…”

Section: Discussionmentioning

confidence: 99%

Use of Fluorescent Indocyanine Green Angiography During Microsurgical Resection of a Recurrent Giant Perimedullary Cervical Spinal Arteriovenous Fistula in a Patient with Hereditary Hemorrhagic Telangiectasia: A Case Report

Choudhri¹,

Heit²,

Gupta³

et al. 2014

Cureus

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We report the utility of fluorescent indocyanine green (ICG) during the microsurgical resection of a giant perimedullary cervical arteriovenous fistula (GPMAVF) in a young man with hereditary hemorrhagic telangiectasia. ICG angiography is a useful adjunct for understanding angioarchitecture and drainage patterns in spinal arteriovenous malformation (AVM) surgery. Cervical GPMAVF is a rare spinal lesion found in association with hereditary hemorrhagic telangiectasia. This vascular malformation is associated with venous varices in a perimedullary location causing cord compression and vascular steal. This rare case highlights the crucial role of ICG during complex spinal AVM/AVF surgery to obtain angiographic cure.

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Intraoperative Indocyanine Green Video-Angiography

Abstract: Intraoperative ICG video-angiography serves an important role in the microsurgical treatment of DAVF. It is simple and provides real-time information about the precise location of spinal DAVF and result after obliteration of spinal DAVF.

Cited by 26 publications

References 9 publications

Intraoperative Near-infrared Fluorescence Imaging with Novel Indocyanine Green-Loaded Nanocarrier for Spinal Metastasis: A Preliminary Animal Study

Intraoperative Near-infrared Fluorescence Imaging with Novel Indocyanine Green-Loaded Nanocarrier for Spinal Metastasis: A Preliminary Animal Study

Review of avoidance of complications in cerebral aneurysm surgery: The Fujita experience

Use of Fluorescent Indocyanine Green Angiography During Microsurgical Resection of a Recurrent Giant Perimedullary Cervical Spinal Arteriovenous Fistula in a Patient with Hereditary Hemorrhagic Telangiectasia: A Case Report

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