Intraoperative Immunohistochemistry During Mohs Micrographic Surgery and Staged Excision Decreases Local Recurrence Rates for Invasive Cutaneous Melanoma: A Systematic Review and Meta-Analysis
Keegan O'Hern,
Olivia M. Crum,
Addison M. Demer
et al.
Abstract:BACKGROUND
Mohs micrographic surgery (MMS) is increasingly used to treat cutaneous melanoma. However, it is unclear whether intraoperative immunohistochemistry (IHC) improves surgical outcomes.
OBJECTIVE
To determine whether intraoperative IHC during MMS and staged excision is associated with a decreased risk of poor surgical outcomes.
MATERIALS AND METHODS
Search of 6 databases identified comparative and no… Show more
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