Intraoperative identification of parathyroid glands: Appraisal of methylene blue staining

Serotonin syndrome following methylene blue infusion during parathyroidectomy: A case report and literature review

“…9 It is the only dye in common use for intraoperative identification of parathyroid glands, and it relies on accurate timing to deliver the full dose via infusion, in the hour before the operation. 10 The above case is the eighth reported occurrence of an adverse reaction following administration of methylene blue in standard dose for parathyroidectomy. In all eight cases the cause of the patient's condition was unclear.…”

Intraoperative Use of Methylene Blue to Localize Parathyroid Adenoma

“…If any question exists as to the patient's oxygen saturation, a blood gas value can be obtained and oxygenation confirmed. The color of the patient has been described as a pseudocyanosis from the dye; this is a very transient phenomena 11 . The patient's urine will remain intensely stained for a few days.…”

Intraoperative adjuncts in surgery for primary hyperparathyroidism

“…There are no prospective studies published on this topic. Many retrospective studies describe its use [90][91][92][93][94][95][96][97][98][99][100][101][102][103], five of them originating from the same center [104][105][106][107][108]. Two of them showed a small but significant reduction in the duration of surgery [107,109].…”