Intraoperative Core Temperature Patterns, Transfusion Requirement, and Hospital Duration in Patients Warmed With Forced Air

Sun, Zhuo; Honar, Hooman; Sessler, Daniel I.; Dalton, Jarrod E.; Yang, Dongsheng; Panjasawatwong, Krit; Deroee, Armin Farajzadeh; Salmasi, Vafi; Saager, Leif; Kurz, Andrea

doi:10.1097/01.sa.0000482341.86369.e7

Cited by 49 publications

(90 citation statements)

References 29 publications

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“…However, the incidence of perioperative hypothermia in laparoscopic surgery has been found to be comparable to that in patients undergoing open abdominal surgery. 17 In a retrospective study including 58 814 patients, Sun et al 18 recently demonstrated an incidence of hypothermia 3 h after induction of anaesthesia of about 35%. This is lower than our results in the 'no warming' group.…”

Section: Discussionmentioning

confidence: 98%

Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia

Horn

Bein

Broch

et al. 2016

European Journal of Anaesthesiology

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Section: Discussionmentioning

confidence: 98%

Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia

Horn

Bein

Broch

et al. 2016

European Journal of Anaesthesiology

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“…It is well documented that mild hypothermia can prolong coagulation times (Sun et al, 2015). More specifically, in the clinical setting, it has been reported that a decrease in core temperature by 3-4°C may cause a decrease in the enzymatic reactions associated with coagulation and thus increase clotting time (Liu and Yenari, 2007).…”

Section: Discussionmentioning

confidence: 99%

Blood clotting behavior is innately modulated in Ursus Americanus during early and late denning relative to summer months

Iles

Laske

Garshelis

et al. 2016

Journal of Experimental Biology

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Remarkably, American black bears (Ursus americanus) are capable of varying their heart rates to coincide with their breathing, creating pauses of 30 s or more, yet they do not appear to suffer from embolic events. We evaluated some features of the clotting cascade of black bears, providing novel insights into the underlying mechanisms they evoke for embolic protection during hibernation. We measured activated clotting time, prothrombin time and activated partial thromboplastin time during early denning (December), late denning (March) and summer (August). Activated clotting time during early hibernation was ∼3 times longer than that observed among non-hibernating animals. Clotting time was reduced later in hibernation, when bears were within ∼1 month of emerging from dens. Prothrombin time was similar for each seasonal time point, whereas activated partial thromboplastin time was highest during early denning and decreased during late denning and summer. We also examined D-dimer concentration to assess whether the bears were likely to have experienced embolic events. None of the nonparturient bears exceeded a D-dimer concentration of 250 ng ml −1 (considered the clinical threshold for embolism in mammals). Our findings suggest there is unique expression of the clotting cascade in American black bears during hibernation, in which extrinsic pathways are maintained but intrinsic pathways are suppressed. This was evaluated by a significant difference between the activated clotting time and activated partial thromboplastin time during the denning and non-denning periods. These changes are likely adaptive, to avoid clotting events during states of immobilization and/or periods of asystole. However, an intact extrinsic pathway allows for healing of external injuries and/or foreign body responses.

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“…Das Auftreten einer perioperativen Hypothermie erhöht somit die Behandlungskosten [14]. Die intraoperative Inzidenz der perioperativen Hypothermie wird mit bis zu 64 % angegeben und hat eine hohe Relevanz [20].…”

Section: Hintergrundunclassified

Perioperatives Wärmemanagement in Abhängigkeit von der Krankenhausgröße in Deutschland

et al. 2015

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Intraoperative Core Temperature Patterns, Transfusion Requirement, and Hospital Duration in Patients Warmed With Forced Air

Abstract: Background-Core temperature patterns in patients warmed with forced-air remain poorly characterized. Also unknown is the extent to which transient and mild intraoperative hypothermia contributes to adverse outcomes in broad populations.

Cited by 49 publications

References 29 publications

Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia

Warming before and after epidural block before general anaesthesia for major abdominal surgery prevents perioperative hypothermia

Blood clotting behavior is innately modulated in Ursus Americanus during early and late denning relative to summer months

Perioperatives Wärmemanagement in Abhängigkeit von der Krankenhausgröße in Deutschland

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