Intraoperative blood salvage: a review

Kr, Williamson; Hf, Taswell

doi:10.1046/j.1537-2995.1991.31791368347.x

Cited by 126 publications

(49 citation statements)

References 73 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It was shown that the hematocrit and the hemoglobin level could be reduced without increasing morbidity and mortality rates [146][147][148][149], and thus the use of normovolemic hemodilution should be encouraged [146,147]. Future attempts at reducing transfusion with allogeneic and predeposit autologous blood may depend on the clinical effectivity of bone marrow stimulating drugs [150,151], artificial blood products [152], and intraoperative and postoperative shed and reinfused autologous blood, at least in noncontaminated surgery for benign diseases [153][154][155].…”

Section: Prospects For the Futurementioning

confidence: 99%

Clinical Impact of Bioactive Substances in Blood Components: Implications for Leukocyte Filtration

Nielsen¹

1998

Transfus Med Hemother

View full text Add to dashboard Cite

Section: Prospects For the Futurementioning

confidence: 99%

Clinical Impact of Bioactive Substances in Blood Components: Implications for Leukocyte Filtration

Nielsen¹

1998

Transfus Med Hemother

View full text Add to dashboard Cite

“…[1][2][3] Different techniques for autologous transfusions have been developed. Autotransfusion can be subdivided depending on the extent to which the scavenged blood is processed prior to infusion.…”

mentioning

confidence: 99%

Complement split products and pro-inflammatory cytokines in salvaged blood after hip and knee arthroplasty

Andersson

Tylman

Bengtson

et al. 2001

Can J Anesth/J Can Anesth

View full text Add to dashboard Cite

Purpose: To determine whether salvaged autologous blood collected postoperatively contains complement split products (SC5b-9), and pro-inflammatory cytokines (IL-6 and IL-8) and whether there are any differences between blood collected during hip or knee surgery.Methods: Fifty-eight consecutive patients undergoing hip or knee replacement surgery were studied. Thirty-eight had postoperative bleeding large enough to require infusion of salvaged blood. The salvaged blood was filtered during collection through a 200 µm filter and before infusion a 40 µm filter was used. Samples for complement and cytokine determinations were drawn from the circulation and from the collected blood.Results: High concentrations of SC5b-9, IL-6, and IL-8 were found in salvaged blood. The concentrations were higher than in the circulation (P < 0.05). The circulating concentrations of IL-6 and IL-8 were increased 60 min and 12-18 hr after transfusion. There were no differences regarding SC5b-9, IL-6, and IL-8 in the blood collected after hip or knee surgery.Conclusion: Blood collected from a surgical wound contains large concentrations of inflammatory mediators. There were no differences between blood collected during hip or knee surgery.Objectif : Déterminer si la récupération postopératoire de sang autologue contient des produits de dégradation du complément (SC5b-9) et des cytokines pro-inflammatoires (IL-6 et IL-8), et s'il y a des différences avec le sang prélevé pendant l'opération de la hanche ou du genou.Méthode : L'étude a porté sur 58 patients successivement admis pour la mise en place d'une prothèse de hanche ou du genou. Chez 38 d'entre eux, les pertes sanguines postopératoires ont été assez importantes pour néces-siter la transfusion de sang récupéré. Ce sang a été filtré pendant le prélèvement avec un filtre de 200 µm et avant la transfusion avec un filtre de 40 µm. Des échantillons retenus de la circulation et du sang récupéré ont servi à déterminer la cytokine et le complément.

show abstract

“…Electron microscopy reveals only minor alterations in red cell morphology with ICS as red cells maintain near normal survival and 2,3 diphosphoglycerate concentrations. 18 Patient's hemoglobin should be maintained at levels just sufficient to provide adequate oxygenation to the tissues. Perioperative management goal should be always focused toward safe transfusion-free transplantation with zero tolerance for blood loss of any kind.…”

Section: Perioperative Management Of An Organ Transplant Recipientmentioning

confidence: 99%

Transfusion medicine and solid organ transplant – Update and review of some current issues

Sarkar

Philip

Yadav

2013

Medical Journal Armed Forces India

View full text Add to dashboard Cite

Intraoperative blood salvage: a review

Cited by 126 publications

References 73 publications

Clinical Impact of Bioactive Substances in Blood Components: Implications for Leukocyte Filtration

Clinical Impact of Bioactive Substances in Blood Components: Implications for Leukocyte Filtration

Complement split products and pro-inflammatory cytokines in salvaged blood after hip and knee arthroplasty

Transfusion medicine and solid organ transplant – Update and review of some current issues

Contact Info

Product

Resources

About