Intraoperative Acoustic Evaluation of Living Human Cartilage of the Elbow and Knee during Mosaicplasty for Osteochondritis Dissecans of the Elbow

Nishitani, Kohei; Nakagawa, Yasuaki; Gotoh, Tadashi; Kobayashi, Masahiko; Nakamura, Takashi

doi:10.1177/0363546508322898

Cited by 15 publications

(11 citation statements)

References 31 publications

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“…An acoustic evaluation indicates that the properties of the human cartilage in the donor site of the knee are similar to those of the capitellum, even though the cartilage is thicker in the donor site than in the capitellum. 17 On the basis of these experimental data, we speculate that the difference in thickness between host and donor cartilage does not lead to a predisposition toward osteoarthritic changes in the grafted or adjacent cartilage after performing mosaicplasty. Further studies will be needed to confirm this point.…”

Section: Discussionmentioning

confidence: 71%

Sequential Alterations in Magnetic Resonance Imaging Findings After Autologous Osteochondral Mosaicplasty for Young Athletes With Osteochondritis Dissecans of the Humeral Capitellum

et al. 2009

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Section: Discussionmentioning

confidence: 71%

Sequential Alterations in Magnetic Resonance Imaging Findings After Autologous Osteochondral Mosaicplasty for Young Athletes With Osteochondritis Dissecans of the Humeral Capitellum

et al. 2009

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“…The ultrasonic measurement system with noncontact probe has been described previously and provides a quantitative assessment of tissues properties [5], [12], [13]. In brief, the transducer is 3 mm in diameter, and the center frequency of the ultrasonic signal is 10 MHz (Figure 1A).…”

Section: Methodsmentioning

confidence: 99%

“…We developed our ultrasound noncontact method to evaluate the cartilage in an animal model. More recently, an ultrasound noncontact arthroscopy probe was used to evaluate knee and elbow cartilage during surgery [5], [6], [7]. Our recent report shows that the ultrasound signal intensity (US signal intensity) is useful for differentiating normal (ICRS grade 0) from slightly degenerated cartilage (ICRS grade 1) [7].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound Can Detect Macroscopically Undetectable Changes in Osteoarthritis Reflecting the Superficial Histological and Biochemical Degeneration: Ex Vivo Study of Rabbit and Human Cartilage

et al. 2014

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Recognizing subtle cartilage changes in the preclinical stage of osteoarthritis (OA) is essential for early diagnosis. To this end, the ability of the ultrasound signal intensity to detect macroscopically undetectable cartilage change was investigated. In this study, cartilage of rabbit OA model and human OA samples was examined by macroscopic evaluation, ultrasound signal intensity, histology with Mankin scores, and Fourier transform infrared imaging (FTIRI) analysis. Rabbit OA was induced by anterior cruciate ligament transection and evaluated at 1, 2, 4 and 12 weeks. Twenty human samples were harvested during total knee arthroplasty from OA patients who had macroscopically normal human cartilage (ICRS grade 0) on the lateral femoral condyle. In the animal study, there was no macroscopic OA change at 2 weeks, but histology detected degenerative changes at this time point. Ultrasound signal intensity also detected degeneration at 2 weeks. In human samples, all samples were obtained from macroscopically intact site, however nearly normal (0≤ Mankin score <2), early OA (2≤ Mankin score <6), and moderate OA (6≤ Mankin score <10) samples were actually intermixed. Ultrasound signal intensity was significantly different among these 3 stages and was well correlated with Mankin scores (R = −0.80) and FTIR parameters related to collagen and proteoglycan content in superficial zone. In conclusion, ultrasound can detect microscopic cartilage deterioration when such changes do not exist macroscopically, reflecting superficial histological and biochemical changes.

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“…25 This enables accurate scoring of cartilage lesions, unlike conventional arthroscopy which provides no information on cartilage thickness. Quantitative ultrasonic measurements of human articular cartilage have been conducted in vivo during arthroscopy, [27][28][29][30] and the potential of ultrasound arthroscopic imaging has been investigated in human knee joints. 12 However, the suitability of this technique for arthroscopy of the shoulder, a more restricted joint, has not been evaluated.…”

Section: Introductionmentioning

confidence: 99%

In Vivo Evaluation of the Potential of High-Frequency Ultrasound for Arthroscopic Examination of the Shoulder Joint

et al. 2016

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Objective. Accurate arthroscopic evaluation of cartilage lesions could significantly improve the outcome of repair surgery. In this study, we investigated for the first time the potential of intra-articular ultrasound as an arthroscopic tool for grading cartilage defects in the human shoulder joint in vivo and compared the outcome to results from arthroscopic evaluation and magnetic resonance imaging findings. Design. A total of 26 sites from 9 patients undergoing routine shoulder arthroscopy were quantitatively evaluated with a clinical intravascular (40MHz) ultrasound imaging system, using the regular arthroscopy portals. Reflection coefficient (R), integrated reflection coefficient (IRC), apparent integrated backscattering (AIB), and ultrasound roughness index (URI) were calculated, and high-resolution ultrasound images were obtained per site. Each site was visually graded according to the International Cartilage Repair Society (ICRS) system. "Ultrasound scores" corresponding to the ICRS system were determined from the ultrasound images. Magnetic resonance imaging was conducted and cartilage integrity at each site was classified into 5 grades (0 = normal, 4 = severely abnormal) by a radiologist. Results. R and IRC were lower at sites with damaged cartilage surface (P = 0.033 and P = 0.043, respectively) and correlated with arthroscopic ICRS grades (r s = −0.444, P = 0.023 and r s = −0.426, P = 0.03, respectively). Arthroscopic ICRS grades and ultrasound scores were significantly correlated (rs = 0.472, P = 0.015), but no significant correlation was found between magnetic resonance imaging data and other parameters. Conclusion. The results suggest that ultrasound arthroscopy could facilitate quantitative clinical appraisal of articular cartilage integrity in the shoulder joint and provide information on cartilage lesion depth and severity for quantitative diagnostics in surgery.

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Intraoperative Acoustic Evaluation of Living Human Cartilage of the Elbow and Knee during Mosaicplasty for Osteochondritis Dissecans of the Elbow

Abstract: Not only the cartilage of the capitellum but the cartilage of the radial head are acoustically degenerated in osteochondritis dissecans patients. Plugs might be damaged in the transplanting procedure, and further follow-up is necessary.

Cited by 15 publications

References 31 publications

Sequential Alterations in Magnetic Resonance Imaging Findings After Autologous Osteochondral Mosaicplasty for Young Athletes With Osteochondritis Dissecans of the Humeral Capitellum

Sequential Alterations in Magnetic Resonance Imaging Findings After Autologous Osteochondral Mosaicplasty for Young Athletes With Osteochondritis Dissecans of the Humeral Capitellum

Ultrasound Can Detect Macroscopically Undetectable Changes in Osteoarthritis Reflecting the Superficial Histological and Biochemical Degeneration: Ex Vivo Study of Rabbit and Human Cartilage

In Vivo Evaluation of the Potential of High-Frequency Ultrasound for Arthroscopic Examination of the Shoulder Joint

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