Intraocular Pressure Control after Contact Transscleral Diode Cyclophotocoagulation in Eyes with Intractable Glaucoma

Yap-Veloso, Maria Imelda R.; Simmons, Robert B.; Echelman, David A.; Gonzales, Teodoro K.; Veira, Wagner J. X.; Simmons, Richard J.

doi:10.1097/00061198-199810000-00006

Cited by 51 publications

(63 citation statements)

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“…4,22 The results of our study reveal a drop of IOP of about 53%, which compares favourably with the 30-50% range that has been reported in the literature. 5,6,14 The percentage of patients achieving an IOP of 21 mmHg, or less was 75% at 6 months, and 72.2% at the last follow-up; this is also in agreement with the figures of 38-95% in the literature. 5,6 Most importantly, is the maintenance of the pressure lowering effect over the mean follow-up of 14 months, without the need for multiple retreatments.…”

Section: Eyesupporting

confidence: 90%

“…In 25% of the study patients vision improved by 2 or more Snellen lines; 13.8% suffered a comparable loss, while the rest remained unchanged. These are promising figures when compared to those in other studies, 14,17 and this may be partly related to the higher percentage of patients with relatively good visual acuity enrolled in this study. Only few painful eyes with very little vision were included.…”

Section: Eyesupporting

confidence: 54%

“…The combination of several advantages has encouraged several groups to study the various aspects of this treatment. [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16] Some studies have made use of these facts to attempt even primary treatment of high-risk patients, 3,18 and to compare results of cyclophotocoagulation to better-established treatment options, such as filtering surgery, and drainage implants. Unfortunately, most of these studies were retrospective, with significant variability in the energy settings and in the number of applications making comparison and inference quite difficult.…”

Section: Discussionmentioning

confidence: 99%

“…Only one patient (2.7%) developed relative hypotony in this study, compared to a range of 1-2% in the literature. 2,14 It is conceivable that multiple treatment sessions be associated with a higher risk of hypotony, considering their cumulative destructive effect on the ciliary epithelium.…”

Section: Eyementioning

confidence: 99%

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Diode laser transcleral cyclophotocoagulation for refractory glaucoma: a 1 year follow-up of patients treated using an aggressive protocol

Noureddin

Zein

Haddad

et al. 2005

Eye

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Purpose To prospectively evaluate the intraocular pressure (IOP) lowering ability, retreatment rate, and complications of transcleral Diode laser cyclophotocoagulation using a higher power setting than what is generally recommended. Patients and methods A total of 36 eyes of thirty six patients with refractory glaucoma, and who fitted our inclusion criteria underwent Diode cyclophotocoagulation. The laser power was set at 2250 mW, with a duration of 2000 ms, and a total number of 28 shots for the first treatment and 20 shots for any consequent one. The patients were followed up for 1 year with the following outcomes being analysed: IOP, visual acuity, change in the number of medications, and complications. Results The mean IOP decrease was 53% (Po0.05), and 72.2% of the patients maintained an IOP r21 mmHg for the whole duration of the study The number of medications necessary to control the pressure, significantly dropped from 2.8 to 0.89 (Po0.05), and 25% of the patients needed the treatment to be repeated only once. In all, 33% of the patients improved their visual acuity after the treatment, while 22% worsened, and the rest stayed the same. The most common treatment complications were conjunctival injection and corneal oedema, and these were both transient and reversible. Conclusion The use of the higher power setting of 2250 mW, resulted in a sustained lower IOP, less use of medications, less need for retreatment, relative preservation of visual acuity, and only reversible complications.

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Section: Eyesupporting

confidence: 90%

Section: Eyesupporting

confidence: 54%

Section: Discussionmentioning

confidence: 99%

Section: Eyementioning

confidence: 99%

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Diode laser transcleral cyclophotocoagulation for refractory glaucoma: a 1 year follow-up of patients treated using an aggressive protocol

Noureddin

Zein

Haddad

et al. 2005

Eye

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“…Brancato et al (1995) 48 Transscleral 20.7 AE 8 70.8% (IOP < 21 mmHg) Kosoko et al (1996) 27 Transscleral 19 84% (IOP reduction > 20% at 1 year) 62% (IOP reduction > 20% at 2 years) Bloom et al (1997) 210 Transscleral 10 66% (IOP < 22 mmHg) Chen et al (1997) 68 Endoscopic 12.9 90% (IOP < 21 mmHg) Hamard et al (1997) 50 Transscleral 19.4 AE 9.1 66% (IOP < 20 mmHg) Yap-Veloso et al (1998) IOP, intra-ocular pressure.…”

Section: Retreatmentmentioning

confidence: 99%

Multicenter clinical trial of high‐intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery

Aptel

Denis

Rouland

et al. 2015

Acta Ophthalmologica

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ABSTRACT.Purpose: To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma na€ ıve of previous filtering surgery. Methods: Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with open-angle glaucoma, intra-ocular pressure (IOP) > 21 mmHg and with no previous filtering glaucoma surgeries were sonicated with a probe comprising six piezoelectric transducers. The six transducers were activated with a 6-s exposure time. Complete ophthalmic examinations were performed before the procedure and at 1 day, 1 week, 1, 2, 3, 6 and 12 months after the procedure. Primary outcomes were qualified surgical success (defined as IOP reduction from baseline ≥20% and IOP > 5 mmHg with possible re-intervention and without hypotensive medication adjunction) and complete surgical success (defined as IOP reduction from baseline ≥20%, IOP > 5 mmHg and IOP < 21 mmHg with possible re-intervention and without hypotensive medication adjunction) at the last follow-up visit and vision-threatening complications. Secondary outcomes were mean IOP at each follow-up visit compared with baseline, medication use, complications and re-interventions. Results: Intra-ocular pressure was significantly reduced (p < 0.05) from a mean pre-operative value of 28.2 AE 7.2 mmHg (n = 3.6 hypotensive medications) to 19.6 AE 7.9 mmHg at 12 months (n = 3.1 hypotensive medications and n = 1.1 procedures) (mean IOP reduction of 30%). Qualified success was achieved in 63% of eyes (19/30) (mean IOP reduction of 37% in these eyes) and complete success in 46.7% of eyes (14/30) (mean IOP reduction of 37% in these eyes) at the last follow-up. No major intra-or post-operative complications occurred. Conclusions: The UC 3 procedure seems to be an effective and well-tolerated method to reduce IOP in patients with open-angle glaucoma without previous filtering surgery.

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Alteration of the vascular supply in the rabbit ciliary body by transscleral diode laser cyclophotocoagulation

Schlote¹,

Beck²,

Rohrbach³

et al. 2001

Graefe's Arch Clin Exp Ophthalmol

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The vascular casting technique is an excellent method for the investigation of changes in ciliary body vascularization after cyclodestruction. This study is the first to demonstrate a marked rarefication of the ciliary body vascularization after diode laser cyclophotocoagulation using vascular casts. The results suggest that alteration of vascularization probably acts as a strong synergistic mechanism in the decrease of intraocular pressure after cyclophotocoagulation of the pars plicata.

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Intraocular Pressure Control after Contact Transscleral Diode Cyclophotocoagulation in Eyes with Intractable Glaucoma

Cited by 51 publications

References 0 publications

Diode laser transcleral cyclophotocoagulation for refractory glaucoma: a 1 year follow-up of patients treated using an aggressive protocol

Diode laser transcleral cyclophotocoagulation for refractory glaucoma: a 1 year follow-up of patients treated using an aggressive protocol

Multicenter clinical trial of high‐intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery

Alteration of the vascular supply in the rabbit ciliary body by transscleral diode laser cyclophotocoagulation

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