Intraocular pressure change following application of 1% 
tropicamide for diagnostic mydriasis

Effects of Diagnostic Mydriasis with Tropicamide and Phenylephrine on Intraocular Pressure

“…In our study, all participants were adults with a mean age of 44.87±15.94 years. This mean age is similar to that reported in other studies [14,15,24]. Hung et al, and Tsai et al, did a similar study but in children [17,23].…”

“…Other studies with similar results were those of Hung et al, and Shihadeh et al, but these studies were on children and patients with pseudoexfoliation respectively [17,19]. On the other hand, Pukrushpan et al, reported no significant difference in mean IOP pre and post dilatation even though their study population was similar to that of this study [24]. This difference in findings may be because of the use of a single agent and the fact that IOP was rechecked only once at 30 minutes after dilatation therefore, elevations which may have occurred thereafter might have been missed.…”

“…Diagnostic mydriasis using these pharmacological agents is not without consequences. Many studies have shown that pupillary dilatation can cause a change in IOP, most supporting an increase in IOP in normal eyes and also abnormal eyes notably those that are glaucomatous [14][15][16][17][18][19][20][21][22] and others showing no significant change [23,24].…”

Transient changes of intraocular pressure and anterior segment configuration after diagnostic mydriasis with 1% tropicamide in children

“…Pukrushpan, Tulvatana and Kulvichit 21 showed that post‐dilatation IOP in open‐angle, non‐glaucomatous patients undergoing routine diagnostic mydriasis with tropicamide was equivalent to the pre‐dilatation IOP, although there was significant ACA narrowing after mydriasis. In contrast, Marchini and colleagues 22 found that following mydriasis, the angle showed a small widening and IOP rise, which was not significant in normal controls.…”

Effect of mydriasis induced by topical instillations of 0.5% tropicamide on the anterior segment in normotensive dogs using ultrasound biomicroscopy

“…Tropicamide is commonly used as a diagnostic mydriatic agent because it induces mydriasis of rapid onset and short duration. The effect of pharmacologically induced mydriasis on the intraocular pressure (IOP) has been studied in humans, 4–11 dogs, 12–15 cats, 16,17 and horses 18,19 . In humans, the use of mydriatic agents such as tropicamide, cyclopentolate, or atropine may cause an acute angle‐closure glaucoma in patients in whom the angle is potentially occludable 5,6,9,20 .…”