Intraocular Lenses and Experimental Bacterial Endophthalmitis

Hopen, Gary; Mondino, Bartly J.; Kozy, David; Lipkowitz, Jeffrey

doi:10.1016/0002-9394(82)90369-5

Cited by 22 publications

(3 citation statements)

References 27 publications

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“…Clinically, we do not have the im pression that the posterior capsule is a possible barrier to the spread of postoperative infection from the anterior to the posterior chamber, first because the incidence of endophthalmitis is higher after extracapsular than after intracapsular surgery; second because in all our cases of endophthalmitis we have seen a vit reous involvement and finally because vitreous taps yield more often positive cultures than anterior chamber ones. This is of course in contrast with what has been found experimen tally [6,7].…”

Section: Intraocular Surgerycontrasting

confidence: 54%

Bacteriological Study of 92 Cases of Proven Infectious Endophthalmitis Treated with Pars plana Vitrectomy

Verbraeken¹,

Rysselaere²

1991

Ophthalmologica

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92 cases of proven infectious endophthalmitis underwent pars plana vitrectomy first to identify the responsible agent and directing the antibiotherapy, second to remove the absces and third to make room for intravitreal injection of antibiotics. A wide spectrum of organisms was isolated (16 different agents). Prognosis of endophthalmitis depends on (1) the responsible agent and (2) the reason for developing the endophthalmitis. The prognosis after lens implantation was rather favorable, whereas after vitrectomy the results were disastrous. Good results were obtained if the infecting agent was Staphylococcus epidermidis. Results after Streptococcus, Staphylococcus aureus, Bacillus or Pneumococcus were bad. Of the mycotic cases, only half of the Candida cases were cured. Other mycotic infections had a worse outcome.

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Section: Intraocular Surgerycontrasting

confidence: 54%

Bacteriological Study of 92 Cases of Proven Infectious Endophthalmitis Treated with Pars plana Vitrectomy

Verbraeken¹,

Rysselaere²

1991

Ophthalmologica

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“…epidennidis EO the use of invasive techniques like intravitreal injection and vitrectomy is not warranted. In our opinion it is dficult to arrive at this decision be- (Hopen et al 1982;Zaidman & Mondmo 1982;Driebe et al 1986). This is reflected in the present study wherein only one eye out of 7 with IOL had to be eviscerated.…”

Section: Discussionmentioning

confidence: 95%

Visual outcome of endophthalmitis in Sweden

Koul

Philipson

1989

Acta Ophthalmologica

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A retrospective study of 62 cases of clinically diagnosed endophthalmitis (EO) reported from 24 clinics in Sweden was carried out. Both culture negative and positive cases were included. The function of the eye was lost in 34% of all cases, while vision better than 0.1 was preserved in 41% cases. Staph. epidermidis positive and culture negative cases were associated with better visual results. The majority of eyes with cultures positive for Staph. aureus were lost or became blind. Intravitreal injection of antibiotics and vitrectomy was generally reserved for more severe cases often involving a delay in their institution. A combination of topical and systemic steroids gave better results than no steroids or only topical steroid administration.

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“…IOL explantation is not necessary in all the cases of pseudophakic endophthalmitis. 8,9 Explantation of the IOL is mostly necessary in fungal endophthalmitis and in P. acnes endophthalmitis, however one should try to preserve IOL as far as possible and perform a generous capsulotomy, either to retain or exchange the IOL and to inject intraocular antibiotic near the remaining part of the capsular bag. 10 IOL explantation should be reserved as a last option.…”

Section: Vitrectomymentioning

confidence: 99%

Pars Plana Vitrectomy in Endophthalmitis

2021

Güncel Retina (Current Retina)

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Developing due to infectious and noninfectious causes, endophthalmitis is a serious condition requiring urgent intervention which can lead to eye loss. In recent years, medical and surgical approaches had great improvement in the treatment of endophthalmitis. Early diagnosis and therapy are very important in endophthalmitis. By prompt and accurate treatment, good outcomes are established. In order to get successful results, the combination of intravitreal antibiotic and pars plana vitrectomy approach is the best treatment modality. Early pars plana vitrectomy eliminates infective agents, suitable media, and toxins while amplifying the action of intravitreal antibiotics.

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Intraocular Lenses and Experimental Bacterial Endophthalmitis

Cited by 22 publications

References 27 publications

Bacteriological Study of 92 Cases of Proven Infectious Endophthalmitis Treated with Pars plana Vitrectomy

Bacteriological Study of 92 Cases of Proven Infectious Endophthalmitis Treated with Pars plana Vitrectomy

Visual outcome of endophthalmitis in Sweden

Pars Plana Vitrectomy in Endophthalmitis

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