Intraocular lenses and anticoagulation and antiplatelet therapy

Stone, Larry; Kline, Oram R.; Sklar, Craig

doi:10.1016/s0146-2776(85)80013-6

Cited by 68 publications

(27 citation statements)

References 3 publications

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“…Cataract surgery does not seem to have an adverse outcome in patients on APACT. [2][3][4] Despite this a proportion of ophthalmic surgeons discontinue such therapy before cataract surgery resulting in serious systemic thromboembolic complications. 2,4 Parkin and Manners 5 showed considerable variation in practice among consultant ophthalmologists regarding stopping and continuing with APACT therapy during oculoplastic surgery.…”

Section: Introductionmentioning

confidence: 99%

“…[2][3][4] Despite this a proportion of ophthalmic surgeons discontinue such therapy before cataract surgery resulting in serious systemic thromboembolic complications. 2,4 Parkin and Manners 5 showed considerable variation in practice among consultant ophthalmologists regarding stopping and continuing with APACT therapy during oculoplastic surgery. In their study, half of the surgeons questioned would consider stopping warfarin before oculoplastic procedures and over half the surgeons had experienced complications relating to both stopping and continuing with aspirin or warfarin therapy.…”

Section: Introductionmentioning

confidence: 99%

“…On the other hand stopping APACT preoperatively may place the patient at risk of lifethreatening arterial embolism. 2,4 In addition to this glaucoma surgery is now no longer a single entity. It may be combined with cataract surgery, application of intra-and postoperative antimetabolites and bleb intervention.…”

Section: Introductionmentioning

confidence: 99%

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The effect of aspirin and warfarin therapy in trabeculectomy

Cobb

Chakrabarti

Chadha

et al. 2006

Eye

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Aim The management of patients on antiplatelet and anticoagulation therapy (APACT) in glaucoma surgery currently has no specific recommendations. We aimed to establish the risk of haemorrhagic complications and surgical outcome in patients on APACT in glaucoma surgery. Methods We retrospectively examined 367 consecutive trabeculectomies performed between 1994 and 1998. Preoperatively 60 (16.4%) patients were on APACT (55 on aspirin and five on warfarin). The incidence of hyphaema and haemorrhagic complications between patients with and without APACT was documented. Surgical success was defined in two categories as an intraocular pressure (IOP) o21 mmHg and an IOP o16 mmHg 2 years following trabeculectomy with and without antiglaucoma medication. Results None of the patients on aspirin suffered significant intra or postoperative haemorrhage. Aspirin was associated with a significantly higher risk of hyphaema (P ¼ 0.0015) but this was not found to significantly affect IOP control at 2 years. Patients on warfarin suffered haemorrhagic complications and trabeculectomy failure. Conclusions Aspirin appears to be safe to continue with during trabeculectomy. Patients on aspirin have an increased risk of hyphaema following trabeculectomy. This however does not appear to affect surgical outcome. Warfarinised patients are at risk of serious bleeding complications. They require careful monitoring pre-and postoperatively and are at risk of trabeculectomy failure.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The effect of aspirin and warfarin therapy in trabeculectomy

Cobb

Chakrabarti

Chadha

et al. 2006

Eye

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“…These studies concluded that the preoperative discontinuation of blood thinners is not necessary. Potential disadvantages of discontinuing blood thinners before operation include an increased risk of thromboembolic complications, [6][7][8][9] and additional inconvenience and cost for the patient, who must often have laboratory tests monitored and coordinate extra visits with the primary care physician or cardiologist.…”

mentioning

confidence: 99%

Surgical pearl: the use of the CoaguChek S system for the preoperative evaluation of patients taking warfarin

Gloster

Twersky

2004

Journal of the American Academy of Dermatology

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“…In 1985, Stone et al published the results of an enquiry among the 200 members of the American Intra-ocular Implant Club[3]. The majority, 75% of the 135 eye surgeons who replied to the questionnaire, stopped ACT before cataract operation.…”

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confidence: 99%

Anticoagulant therapy and cataract surgery

1989

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A questionnaire was sent round to the 200 members of the Netherlands Intraocular Implant Club (NIOIC), in which they were asked about the policy followed in 1988 with regard to anticoagulant therapy (ACT) and the use of aspirin before and after cataract surgery. Ninety-nine formulas were returned, of which ninety-two were suitable for analysis. It appeared that 62% of the eye surgeons stopped ACT, whereas only 33% stopped the use of aspirin. After stopping ACT nine, in some cases serious, systemic complications arose. The continuation of ACT led to 3 ocular complications. It would appear that continuation of ACT and the use of aspirin is to be recommended.

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Intraocular lenses and anticoagulation and antiplatelet therapy

Cited by 68 publications

References 3 publications

The effect of aspirin and warfarin therapy in trabeculectomy

The effect of aspirin and warfarin therapy in trabeculectomy

Surgical pearl: the use of the CoaguChek S system for the preoperative evaluation of patients taking warfarin

Anticoagulant therapy and cataract surgery

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