Intraocular Inflammations

Naumann, G. O. H.; Naumann, Ludmila

doi:10.1007/978-1-4613-8525-7_4

Cited by 5 publications

(2 citation statements)

References 312 publications

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“…Recently, studies have lead to the realization that another property of space: vacuum, can be significantly utilized for materials processing [3,4] especially in the area of thin-film growth. Thin-film growth of crystalline materials, described as epitaxial thin-film growth, has risen to importance recently due to the major promise of enhanced materials properties in present, and new and unique materials systems [5,6].…”

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confidence: 99%

Epitaxial Thin-Film Crystal Growth in Space Ultra-Vacuum

Ignatiev

1988

Advanced Materials and Manufacturing Processes

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A new concept for materials processing in space with the expectation of future manufacturing in that environment exploits the ultra-vacuum component of space for thin-film epitaxial growth. The unique low earth orbit space environment is expected to yield vacuum levels of 10-14 torr or better, semi-infinite pumping speed and large ultra-vacuum volume (lO's to 100's of cubic meters) without walls. These space ultra-vacuum characteristics promise major improvement in the quality, throughput, and new materials and devices possibilities of epitaxially grown thin films, especially in the area of semiconductors for microelectronics use. For such improved crystalline thin-film materials there is expected a very large value added from space ultra-vacuum processing, and as a result the application of the epitaxial thin-film growth technology to space could lead to major commercial efforts in space. INTRODUCI10NThe use of space for materials processing and possible advanced manufacturing has been proposed for some time. A moderate number of proof-of-concept experiments in this area have been undertaken in the space environrnentlLf], however, they have been generally limited to the use of the micro-gravity aspect of 599

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confidence: 99%

Epitaxial Thin-Film Crystal Growth in Space Ultra-Vacuum

Ignatiev

1988

Advanced Materials and Manufacturing Processes

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“…The maintenance of mitotic quiescence of lens epithelial cells is important for lens shape, size, and clarity (Naumann and Naumann, 1986). Why the majority of lens epithelial cells remain in the Go phase of the cell cycle, even in presence of a multitude of ocular fluid mitogens is not yet known.…”

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Growth regulation of the mammalian ocular lens by vitreous humor

Banerjee

Parafina

Bagchi

1992

J of Cellular Biochemistry

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Experiments were performed in our laboratory to study the effects of a mammalian 8 kD vitreous humor (VH) factor on the DNA synthesis and mitosis of the epithelial cells of organ cultured rabbit lens. The 8 kD polypeptide factor was purified from mature rabbit vitreous humor by liquid chromatography. Proliferative activities of the epithelial cells of organ cultured lenses were stimulated by 3% rabbit serum. The data from our experiments depicted that the 8 kD VH factor effectively inhibits DNA synthesis and mitosis by the epithelial cells of the organ cultured lens. Our experiments also showed that this 8 kD VH factor can maintain its growth inhibitory activity even when heated for 3 min at 95 degrees C. The growth inhibitory effect of the 8 kD VH factor was dose dependent. Using iodinated vitreal proteins it was demonstrated that the VH proteins are able to enter or bind to lens epithelial cells. The growth inhibitory effect of the 8 kD VH factor was also tested on tissue cultured lens epithelial cells. These experiments showed that the 8 kD VH factor has no growth inhibitory effect on the tissue cultured lens epithelial cells. This experiment has been repeated many times using different concentrations of the factor. These observations suggest that the 8 kD VH factor may have receptors in the lens capsular material (extracellular matrix) and the factor-receptor binding is essential for the growth inhibitory effect.

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Ocular Manifestations

Schönherr¹,

Strle²

1993

Aspects of Lyme Borreliosis

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Intraocular Inflammations

Cited by 5 publications

References 312 publications

Epitaxial Thin-Film Crystal Growth in Space Ultra-Vacuum

Epitaxial Thin-Film Crystal Growth in Space Ultra-Vacuum

Growth regulation of the mammalian ocular lens by vitreous humor

Ocular Manifestations

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