Intraneural Synovial Sarcoma of the Median Nerve

Chesser, T.J.S.; Geraghty, J.M.; Clarke, A. M.

doi:10.1054/jhsb.1999.0067

Cited by 25 publications

(19 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…19 To the best of our knowledge, there have only been five cases of intraneural synovial sarcoma (INSS) reported in the literature. [20][21][22][23][24] Three of these cases were seen in teenagers (all 16 years old), while one occurred in a 23-year-old female patient and one occurred in a 43-year-old man. All patients presented with a subcutaneous soft-tissue mass involving major nerve trunks (the popliteal nerve, 23 common digital nerve, 20 median nerve 22 and radial nerve 24 ) often near body surfaces 21 with a frequent history of a previous trauma.…”

mentioning

confidence: 99%

“…[20][21][22][23][24] Three of these cases were seen in teenagers (all 16 years old), while one occurred in a 23-year-old female patient and one occurred in a 43-year-old man. All patients presented with a subcutaneous soft-tissue mass involving major nerve trunks (the popliteal nerve, 23 common digital nerve, 20 median nerve 22 and radial nerve 24 ) often near body surfaces 21 with a frequent history of a previous trauma. Four of the five tumors exhibited histologic and immunohistochemical features of a biphasic SS [20][21][22][23] and one was a monophasic SS.…”

mentioning

confidence: 99%

“…All patients presented with a subcutaneous soft-tissue mass involving major nerve trunks (the popliteal nerve, 23 common digital nerve, 20 median nerve 22 and radial nerve 24 ) often near body surfaces 21 with a frequent history of a previous trauma. Four of the five tumors exhibited histologic and immunohistochemical features of a biphasic SS [20][21][22][23] and one was a monophasic SS. 24 Molecular studies were not performed in these cases.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Intraneural synovial sarcoma: two cases

et al. 2004

View full text Add to dashboard Cite

We report two cases of intraneural synovial sarcoma. The first patient is a 46-year-old female who presented for several months with soft-tissue mass in the right infra-auricular region. The second patient is a 11-year-old girl who fell and then presented with pain in the area innervated by the right C7 spinal root and a nodule identified in the nerve root foramina. Both lesions were of small size and presented with features of synovial sarcoma. A biphasic variant was found in case 1 and a monophasic variant was present in case 2. Immunohistochemical studies were performed to confirm the diagnosis, excluding the main differential diagnoses, namely schwannoma and malignant peripheral nerve sheath tumor. Ultrastructural study was performed in case 2 allowing exclusion of other possible diagnoses. Molecular studies were performed on paraffin-embedded tissue in both cases and revealed the known characteristic t(X;18)(SYT-SSX) translocation.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Intraneural synovial sarcoma: two cases

et al. 2004

View full text Add to dashboard Cite

show abstract

“…Intraneural synovial sarcomas are extremely rare in the main nerve trunks of the upper limb [4,7,26,32]. They were originally thought to originate from synovial membrane; however, less than 5% are microscopically in continuity with the synovium [9].…”

Section: Discussionmentioning

confidence: 99%

“…They may occur at any age but are more prevalent in young adults, and the extremities are the commonest site. In the upper limb, they can be confused clinically with a ganglion [4,10].…”

Section: Discussionmentioning

confidence: 99%

A 56-year-old Woman with a Right Arm Mass

Papagelopoulos¹,

Mavrogenis²,

Skarpidi

et al. 2008

Clinical Orthopaedics &Amp; Related Research

View full text Add to dashboard Cite

A 56-year-old woman was admitted for a 5-year history of a painless right arm mass. The patient denied any recent enlargement. However, over the previous 2 years, the patient complained of gradually increasing numbness at the thumb, index finger, and middle finger of the ipsilateral arm. There was no history of trauma. Medical and family history was unremarkable.Physical examination revealed a soft, oval, deep palpable mass on the medial side of her right arm with a maximum diameter of 4 cm (Fig. 1). Passive and active range of motion of the right elbow and hand were unaffected. Neurologic examination was normal. Routine laboratory analysis including complete blood cell count, serum chemistries, erythrocyte sedimentation rate, and C-reactive protein were within normal limits.We performed plain radiography ( Fig. 2), ultrasonography (Fig. 3), and MRI (Fig. 4).Based on the history, physical examination, laboratory tests, and imaging studies, what is the differential diagnosis? Imaging InterpretationA frontal radiograph of the right upper arm showed a cluster of rounded calcifications in the soft tissues along the medial aspect of the mid humerus. No underlying osseous abnormality was noted (Fig. 2).Ultrasonography of the right arm showed a well-defined oval mass with heterogeneous internal echogenicity. The mass was closely related to the median nerve. Doppler examination revealed a moderate degree of vascularity within the lesion (Fig. 3).MRI showed a fusiform lesion with well-circumscribed borders along the posteromedial aspect of the biceps. The lesion was intermuscular and centered along the expected course of the median nerve. The normal median nerve could not be identified as a distinct structure at this level. The lesion was heterogeneous and slightly hypointense to muscle on T1-weighted images (Fig. 4A-B) and heterogeneously hyperintense on T2-weighted images. On postcontrast T1-weighted images (Fig. 4C-D), the mass enhanced in fairly uniform fashion. Differential Diagnosis Hemangioma SchwannomaEach author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article. Each author certifies that his or her institution has approved the reporting of this case and that all investigations were conducted in conformity with ethical principles of research.

show abstract

Transient forearm conduction block in the median nerve

2002

View full text Add to dashboard Cite

We present two cases referred for electrophysiological confirmation of carpal tunnel syndrome (CTS). Initial nerve conduction studies were normal. Approximately 20 min into the examination, both patients developed sensory symptoms and weakness in the distal median nerve territory while the elbow was extended and forearm supinated. Further studies demonstrated complete conduction block across the forearm in the median motor and sensory nerve fibers. When measurable, conduction velocities remained normal or were modestly slow. Complete clinical and electrophysiological recovery occurred within 2 min following forearm pronation, suggesting that dysfunction was probably due to focal transient ischemia. Patients describing increased sensory symptoms during routine electrophysiological assessments for CTS should be investigated to rule out the possibility of a more proximal abnormality.

show abstract

Intraneural Synovial Sarcoma of the Median Nerve

Cited by 25 publications

References 4 publications

Intraneural synovial sarcoma: two cases

Intraneural synovial sarcoma: two cases

A 56-year-old Woman with a Right Arm Mass

Transient forearm conduction block in the median nerve

Contact Info

Product

Resources

About