IntroductionIntraneural lipomas and lipofibromas (also called lipofibromatous hamartomas) are
rare, benign tumours occurring in peripheral nerves in the forearm and wrist. They
usually present as asymptomatic masses, but if they are large enough, they may cause
symptoms of compression neuropathy. Intraneural lipomas and lipofibromas differ with
regard to anatomy and clinical behaviour: the former tumour has a well-defined
capsule and most commonly occurs within the median nerve in the forearm and wrist.
It is diagnosed in the fourth and fifth decades of life and seen more frequently in
women. The latter (lipofibroma) has no capsule, is infiltrative in nature, is
composed of fatty and fibrous tissue and also most commonly seen in the median
nerve. It occurs in a younger age group with no sexual predominance. Due to these
differences, these lesions are managed differently 1
2.