2017
DOI: 10.1002/lary.27069
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Intranasal tissue necrosis associated with opioid abuse: Case report and systematic review

Abstract: Intranasal opioid abuse is a prevalent condition associated with chronic pain and tissue necrosis that is clinically concerning for invasive fungal disease. Whereas IFRS must be excluded, even in patients without known immunodeficiency, complete resolution of symptoms can be expected following surgical debridement with cessation of opioid abuse. Laryngoscope, 1767-1771, 2018.

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Cited by 2 publications
(2 citation statements)
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“…Tissue necrosis has also been associated with intranasal opioid and acetaminophen abuse 93–95 . Possible mechanisms of injury include hyperosmotic conditions, vasculitic‐like inflammation, or direct injury secondary to talc 95,96 …”
Section: Definitions Classification and Differential Diagnosis Of All...mentioning
confidence: 99%
“…Tissue necrosis has also been associated with intranasal opioid and acetaminophen abuse 93–95 . Possible mechanisms of injury include hyperosmotic conditions, vasculitic‐like inflammation, or direct injury secondary to talc 95,96 …”
Section: Definitions Classification and Differential Diagnosis Of All...mentioning
confidence: 99%
“…For instance, cleft lip and palate is a congenital anomaly (developmental), while medical issues such as oral cancers, neurological damage, and structural injuries are acquired deficits. One type of structural injury is that of palatal lesions due to substance abuse (Hardison et al, 2015;Morrison et al, 2017;Peyriere et al, 2013;Ruscello et al, 2016). Abuse of illegal drugs or misuse of prescription drugs is a significant problem in the United States and eradicating the problem is a primary concern (Banken, 2004;Wilson et al, 2020).…”
mentioning
confidence: 99%