Intramuscular Sodium Methohexital as a Sole Pediatric Anesthetic-Analgesic Agent

Abstract

ODIUM xnethohexital ILW bem used M an S ultmshort.ncting geruml anesthetic and .as an adjunct to 0th-drugs in longer antasthccic procedures for uwr n dccnde.' " Ab-.wnm ut severe cardiovascular dkturbancea and dwrt duration of action have I d to its ust in dentistry RS 10 W e have found rni!thotu?xibl, injcxtctcd intramuscularly, cspccicllly useful in pcdiutric anesthesia, giving a smooth induction, and, limcd judicinudy, muainl: the child to full mlrwp junt :is he reaches the operatinfl theater.11-12 'l'hc uniformly successful results, mpccially in smlIer c h i l h n . h s I d us to use mcthohcxitnl intnirnuscularly as the principal hypnotic a p n t in pediatric urology, especially urelluocystugniphiea, which do not demand prolonfied or profound uwlgeesin. This procedure usually rcquirca only i l short pcriod of rclcrtivo analgesin for introduction of irwbumcnts, and R lonfier period of hypnosis during which radiologic or mnomctric s t u b CM bc rmde. C,wtoIrcoyim, however, have pmved difficvlt under methohexitrrl alonc, a 9 they involve continuous stimulation. h c ! x p a 4 4 thew him hmn a reaction, vuying in degree, to the first painful dimu h , followed by quiet sleep until the examination was completed. Similur ~qucmtxa wen? seen in a separate pediatric orthoyodic series, t h e child reacting during the moment of reposition of fracture or dislcmtion, and thm sleeping while tlie plaster c m t was applied and radiograms taken. MATERIALS AND MLTHODS Urethrwyshgraphies under m t h o h i t u l in the present scrim w c r~ pcrfcmmd on 104

Use of Intravenous Methohexital as a Sedative in Pediatric Emergency Departments

“…Its use in children for induction of anesthesia has been demonstrated via the rectal, intramuscular, and IV routes. [15][16][17][18] The pharmacokinetics of methohexital have been studied in humans, particularly in children. 19,20 Methohexital has been used in adult emergency departments and has been found to produce rapid and brief sedation, especially for orthopedic procedures.…”

Narkoseeinleitung bei Kindern durch intramuskuläre Verabreichung von Methohexital

“…und sollen nach unserer Ansicht von einem postoperativen Nachschlaf profitieren. Auch wird bei uns das Methohexital nie als Alleinnarkotikum in repetierten Dosen verabreicht (10,16).…”