“…Submucosal bleeding and intramural dissection of the esophageal wall, giving rise to an intramural hematoma, has been described as resulting from emetics [9][10][11][12][13][14][15][16], after ingestion of a foreign body and endoscopic instrumentation [17], following remote trauma [18], or as a spontaneous event in patients with impaired hemostasis such as in thrombocytopenia [13,15,19,20], in hemophiliacs [21], and in patients receiving anticoagulation therapy [14,15,17,22], as well as in patients with normal hemostasis [9,16,23,24]. In contrast to patients with a Mallory-Weiss laceration, who present with signs of upper gastrointestinal bleeding with or without pain [l 1], and patients with Boerhaave's syndrome, who present with excruciating pain in the thorax or upper abdomen, signs of circulatory collapse, and often subcutaneous or mediastinal emphysema [11], patients with intramural esophageal hematoma present with a sudden onset of a triad of symptoms: dysphagia, odynophagia, and hematemesis [13,15,24].…”