2000
DOI: 10.1080/028418500127345929
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Intramedullary tuberculomas: MR findings in seven patients

Abstract: Hypo- or iso-intensity on T2WI within the spinal cord with surrounding hyperintense oedema is suggestive of intramedullary tuberculomas. Central hyperintensities are also detected at times due to a variable amount of caseous necrosis with liquefaction. On T1WI, fusiform swelling of the cord is seen along with iso- to hyperintense foci, surrounded by hypointense oedema of the cord. Such findings should prompt a contrast-enhanced study, which may show single or conglomerate disc- or ring-enhancing lesions. MR th… Show more

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Cited by 36 publications
(23 citation statements)
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“…The MRI features of tuberculomas are distinct from other intramedullary lesions and are reliable enough to start antituberculous therapy. 8 Some of these lesions may resolve completely with antituberculous therapy only, 14 but may expand during chemotherapy. 15 Preoperative antituberculous therapy for 1-2 weeks may avoid spreading of intraoperative tuberculosis.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The MRI features of tuberculomas are distinct from other intramedullary lesions and are reliable enough to start antituberculous therapy. 8 Some of these lesions may resolve completely with antituberculous therapy only, 14 but may expand during chemotherapy. 15 Preoperative antituberculous therapy for 1-2 weeks may avoid spreading of intraoperative tuberculosis.…”
Section: Discussionmentioning
confidence: 99%
“…With the development of caseation, the centre becomes bright and gives an appearance of 'target sign'. 7,8 The 'target sign' was thought to be a characteristic sign on the radiological image. 5 Sharma et al 5 reported all their lesions showed marked enhancement on gadolinium injection and central hypointensity with peripheral ring enhancement was seen in five out of eight cases.…”
Section: Discussionmentioning
confidence: 99%
“…In rare cases, areas of diminished attenuation are seen, which represent caseous necrosis. The latter may be identified as tuberculoma, a nodule with a relatively low signal intensity in comparison with that of other pulmonary nodules on T2-weighted SE or turbo SE images (Sakai et al 1992;Kono et al 1993;Kusumoto et al 1994;Parmar et al 2000;Chung et al 2000;Schaefer et al 2006). In addition, several investigators have reported on typical MR findings of tuberculoma on post-contrast-enhanced T1-weighted images known as "thin-rim enhancement" sign (Sakai et al 1992) (Fig.…”
Section: Tuberculomamentioning
confidence: 97%
“…3,7,10,11) The MR imaging appearance of intramedullary tuberculomas changes according to the stage of tuberculoma formation. [4][5][6] In the early phase, inflammatory reaction with variable amounts of peripheral edema is present without the development of a collagenous capsule.…”
Section: Discussionmentioning
confidence: 99%