Intramedullary nails in the treatment of the distal radius fractures

Persoons, Dominique

doi:10.1007/s00590-018-2226-7

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Various genetic mutations have been considered to contribute to BMD alterations [10] . Although many therapeutic methods have been used for osteoporosis, the outcomes of the patients are still poor [11,12] . Therefore, it is necessary to find genetic factors associated with BMD and osteoporosis fracture.…”

Section: Introductionmentioning

confidence: 99%

Genetic association between bone mineral density and the fracture of distal radius

Li¹,

Fu²,

Gao³

et al. 2021

Medicine

View full text Add to dashboard Cite

Low bone mineral density (BMD) was significantly related to the fracture of distal radius. Serum brain-derived neurotrophic factor (BDNF) level was closely related to BMD in spine and osteoporotic fractures. In this study, we aimed to explore the association of BDNF polymorphisms (rs6265 and rs7124442) with BMD and the fracture of distal radius. This retrospective study included 152 patients with distal radius fractures and 148 healthy controls. BDNF polymorphisms were detected via TaqMan allelic discrimination assay. BMD was evaluated through X-ray. Difference in features between cases and controls were compared adopting Chi-square test or t test. The associations of BDNF polymorphisms with fracture risk of distal radius and BMD were assessed employing χ 2 test and expressed by odd ratios (ORs) with 95% confidence intervals (95% CIs). BMD was significantly decreased in patients with the fracture of distal radius than in healthy controls. The polymorphism rs6265 significantly increased the risk of distal radius fracture (adjustment: GA: OR = 1.724, 95%CI = 1.003 –2.951, P = .049; GG: OR = 2.415, 95%CI = 1.0219 –3.674, P = .005). Moreover, rs6265 genotypes GA (OR = 4.326, 95%CI = 1.725 –11.896, P = .003) and GG (OR = 13.285, 95%CI = 3.659 –51.072, P = .001) significantly increased BMD reduction. However, BDNF polymorphism rs7124442 had no obvious correlation with BMD or fracture risk. BMD was associated with BDNF rs6265 polymorphism. BDNF polymorphism rs6265 could elevate the risk of osteoporosis and distal radius fracture.

show abstract

Section: Introductionmentioning

confidence: 99%

Genetic association between bone mineral density and the fracture of distal radius

Li¹,

Fu²,

Gao³

et al. 2021

Medicine

View full text Add to dashboard Cite

show abstract

“…The simplicity, the efficiency and the low cost of the surgical procedure are decisive factors in terms of public health. Therefore, their mechanism should better be fully understood [3][4][5]. The challenge in the Colle's fractures is to maintain an appropriate reduction when the spongious bone is collapsed.…”

Section: Introductionmentioning

confidence: 99%

Preliminary results of new elastic mini-nail in the distal radius fractures. First 83 cases of the nail-o-flex nail

Persoons¹

2019

Asp Biomed Clin Case Rep

View full text Add to dashboard Cite

The distal radius fracture is a common injury in old persons. His treatment remains a critical challenge because of number of cases, the final cost of the procedure, the level of X-rays irradiation and a demanding technic of fixation in osteoporotic bone. The entire closed procedure requires a strict percutaneous nailing. This offers advantages in terms of post-operative pain, per-operative irradiation and cost. The main problem was so far the ability to insure a stable reduction in time. This point is discussed with the introduction of the "Nail-oflex ® " nail. A continuous series of 83 patients is introduced.

show abstract

Intramedullary nails in the treatment of the distal radius fractures

Cited by 2 publications

References 10 publications

Genetic association between bone mineral density and the fracture of distal radius

Genetic association between bone mineral density and the fracture of distal radius

Preliminary results of new elastic mini-nail in the distal radius fractures. First 83 cases of the nail-o-flex nail

Contact Info

Product

Resources

About