Intraluminal oxygen can keep small bowel mucosa intact in a segmental ischemia model
Guido Trentadue,
Peter B. F. Mensink,
Claudius Kruse
et al.
Abstract:Intestinal preservation for transplantation is accompanied by hypoperfusion with long periods of ischemia with total blood cessation and absolute withdrawal of oxygen leading to structural damage. The application of intraluminal oxygen has been successfully tested in small-animal series during storage and transport of the organ but have been so far clinically unrelatable. In this study, we tested whether a simple and clinically approachable method of intraluminal oxygen application could prevent ischemic damag… Show more
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