Intralesional use of amphotericin B associated with oral itraconazole for the treatment of recurrent sporotrichosis in a cat – case report

Abstract

Nasal sporotrichosis is a condition of difficult clinical resolution, which is commonly refractory to treatment and recurrent in cats. In this report, amphotericin B was used intralesionally in combination with oral itraconazole (100 mg/per cat/oral each 24h) in order to treat a cat with relapse of nasal sporotrichosis. During the treatment, laboratory tests were performed to ensure the safety of the protocol used. The new biomarker for renal function SDMA IDEXX was used before and after the end of the protocol to monitor renal function. Adverse effects were edema and local discomfort. Total treatment duration was 3 months, and no renal toxic effect was observed. This protocol therefore proved to be effective and safe to treat nasal sporotrichosis.