Intralesional Triamcinolone Acetonide in the Treatment of Traction Alopecia

Uwakwe, Laura N; Souza, Brianna De; Tovar‐Garza, Andrea; McMichael, Amy J.

doi:10.36849/jdd.2020.4635

Cited by 11 publications

(7 citation statements)

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“…e finding of retained hairs along the frontal and/or temporal hairline ("fringe sign") can help in making a clinical diagnosis of TA [24]. Apart from avoiding all the practices that lead to TA, treatment options have included intralesional corticosteroids directed at the periphery of hair loss to suppress perifollicular inflammation [25], antibiotics used early in the disease for their anti-inflammatory effect [26], minoxidil [27], and hair transplantation.…”

Section: Introductionmentioning

confidence: 99%

A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases

Umar

Carter

2021

Case Reports in Dermatological Medicine

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Introduction. Current approved medications for hair loss, such as topical minoxidil and oral finasteride, may have suboptimal efficacy or side effects precluding continued use in some patients. Thus, we report an evaluation of the efficacy, safety, and tolerability of a new topical botanical formulation -GASHEE containing over 12 phytoactive ingredients that affect multiple targets in the cascade of pathophysiologic events that cause hair loss. Five patients with various hair-loss conditions, including cases of previous treatment failures, are presented. Case Presentation. This is a case series of four women and one man with hair loss due to various causes, four of whom had failed minoxidil treatment for over a year. All patients used the topical treatment as a sole therapy for at least 3 months before the documentation of outcomes, which involved interval changes noted through each patient’s account, direct observation, and photography. Discussion. In all patients, we observed significant improvements in hair regrowth in the nape, crown, vertex, and temple areas after 3–15 months of treatment. All patients were highly satisfied with their results and reported no adverse events. Although the use of botanicals in the treatment of hair loss is in an infant stage, the new formulation used in this study demonstrated a good efficacy related to hair growth, warranting further evaluation.

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Section: Introductionmentioning

confidence: 99%

A Multimodal Hair-Loss Treatment Strategy Using a New Topical Phytoactive Formulation: A Report of Five Cases

Umar

Carter

2021

Case Reports in Dermatological Medicine

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“…Treatment of inflammation/pustules can include intralesional and topical steroids and topical or oral antibiotics for an anti-inflammatory effect. 33,34 The efficacy of these is mixed and requires more rigorous investigations to demonstrate their benefit.…”

Section: Manag Ementmentioning

confidence: 99%

Review of traction alopecia in the pediatric patient: Diagnosis, prevention, and management

Afifi

Oparaugo

Hogeling

2021

Pediatric Dermatology

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Hairstyles and practices are a means of self-expression and can be associated with culture, religion, occupation, and recreational activities. [1][2][3][4][5][6][7][8][9][10][11] Additionally, certain hair practices are a result of lifestyle preferences and the need for a low-maintenance hair routine. Specific hairstyles and practices that frequently apply tension to the hair follicle can result in traction alopecia (TA), which in the early stages is reversible. Prolonged and repeated tension on the hair follicle can result in permanent hair loss. Thus, the most important aspect of management is early recognition and intervention through prevention.Many of the hairstyles and hair practices associated with a higher risk of TA are often first introduced at a young age, making early intervention and education specifically advantageous in the pediatric population. In younger pediatric patients, specific hairstyles may be preferred by parents due to their convenience, low maintenance, and ability to avoid tangling as well as for cultural, religious and recreational purposes. The true prevalence of TA in the pediatric population is likely unknown as TA in this population can be misdiagnosed and unrecognized until adulthood. 1 Pediatric dermatologists in addition to other pediatric providers have the opportunity to counsel patients early and discuss strategies that can minimize damage while still maintaining preferred hairstyles and practices that align with the patient and family's culture, religious beliefs, recreational activities, lifestyle, and self-expression. Here, we provide an inclusive overview of pediatric TA discussing pathophysiology, high-and low-risk hairstyles, diagnosis, prevention strategies, and treatment options. | PATHOPHYS IOLOGYTA is hair loss related to frequent tension on the hair root resulting in mechanical damage to the hair follicle and dermal papilla, which houses the stem cells for new hair growth. 12 Additionally, the application of tension on chemically relaxed or thermally straightened hair can result in a compounded risk for TA. 13 This is thought to be due to weakening of the hair shaft following chemical relaxer treatment resulting in increased breakage and brittleness. 13 Both chemical relaxers and thermal straightening are insufficient to cause TA alone, but they have been shown to be associated with a greater risk of TA with high-tension hairstyles compared with when tension is applied to natural hair. 6,9 Of interest, the pathophysiology of TA is not solely based on environmental exposures. Specific hair phenotype has also been postulated to be associated with increased risk for TA. Structural and biochemical characteristics specific to different hair types/pattern may result in an increased susceptibility to TA. 6,14 Although TA can present in individuals of all racial and ethnic backgrounds, it is increasingly common among patients with a tightcurl pattern and more commonly seen in Black patients. 14,15

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“…To date, most cases have been reported in the scalps of African American women. 3 Here we present a unique case of TA to the frontal chin area of a Hasidic Jewish male.…”

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confidence: 92%