Intralesional bleomycin as alternative therapy in the treatment of multiple basal cell carcinomas

Gyurova, Magdalina; Stancheva, Marieta Zheleva; M, Arnaudova; Yankova, Rumiana Kalopherova

doi:10.5070/d31nw1550f

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion1

Basal Cell Carcinoma1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2009

2024

Publication Types

Select...

Article5

Book1

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 10 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These effects are dose-dependent, and frequent injections of low doses of bleomycin are reported to be the most effective. 33 …”

Section: Discussionmentioning

confidence: 99%

Chemotherapeutical treatment of basal cell carcinoma with bleomycin via microinfusion of the drug into the skin (MMP®)

Pacola¹,

Rostey²,

Rizzo³

2023

Anais Brasileiros de Dermatologia

View full text Add to dashboard Cite

“…These effects are dose-dependent, and frequent injections of low doses of bleomycin are reported to be the most effective. 33 …”

Section: Discussionmentioning

confidence: 99%

Chemotherapeutical treatment of basal cell carcinoma with bleomycin via microinfusion of the drug into the skin (MMP®)

Pacola¹,

Rostey²,

Rizzo³

2023

Anais Brasileiros de Dermatologia

View full text Add to dashboard Cite

“…Recently, the intralesional delivery of bleomycin via micro-infusion (MMP ® ) was introduced and was found to be effective in BCC [33]. There is a case report in which BCC was cleared with intralesional bleomycin injection alone [34].…”

Section: Basal Cell Carcinomamentioning

confidence: 99%

Clinical Efficacy of 5-Fluorouracil and Bleomycin in Dermatology

Kim,

Woo,

Cho

et al. 2024

JCM

View full text Add to dashboard Cite

Bleomycin and 5-fluorouracil (5-FU) are widely used in various dermatological disorders. Both drugs are well-recognized as antineoplastic drugs and exert their effect by blocking the cell cycle. Topical and intralesional formulations are available and have been studied in both non-neoplastic and cancerous lesions. However, data comparing the effect of bleomycin and 5-FU in the dermatological disorders are limited. This review outlines the action mechanisms of both drugs and compares their clinical efficacies in a wide range of dermatologic diseases including hypertrophic scar, wart, skin cancer, vascular malformation, hemangioma, and vitiligo, and discusses the overall safety of the drugs. Intralesional bleomycin treatment is effective in hypertrophic scars and warts, but intralesional 5-FU may also be considered since it is cheaper and less painful. Moreover, intralesional 5-FU and bleomycin injection is a viable option for premalignant lesions (i.e., actinic keratosis) and inoperable skin cancers. Both bleomycin and 5-FU have been applied as treatment adjuncts for vitiligo, with 5-FU showing a slightly better outcome. Both agents have a good safety profile, and no serious side effects have been reported following their use in the field of dermatology.

show abstract

Intralesional Agents to Manage Cutaneous Malignancy

High

2010

Non-Surgical Treatment of Keratinocyte Skin Cancer

View full text Add to dashboard Cite

Intralesional bleomycin as alternative therapy in the treatment of multiple basal cell carcinomas

Cited by 10 publications

References 0 publications

Chemotherapeutical treatment of basal cell carcinoma with bleomycin via microinfusion of the drug into the skin (MMP®)

Chemotherapeutical treatment of basal cell carcinoma with bleomycin via microinfusion of the drug into the skin (MMP®)

Clinical Efficacy of 5-Fluorouracil and Bleomycin in Dermatology

Intralesional Agents to Manage Cutaneous Malignancy

Contact Info

Product

Resources

About