Intralaryngotracheal thyroid – ectopic thyroid or invasive carcinoma?

See, A. C. H.; Patel, Snehal G.; Montgomery, P. Q.; Evans, Peter H.; Fisher, Cyril

doi:10.1017/s0022215100141428

Cited by 24 publications

(13 citation statements)

References 16 publications

(21 reference statements)

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“…The estimated incidence for carcinoma arising in a lingual thyroid is only 1% [20][21][22] . Among the 125 cases of intralaryngotracheal thyroid published prior to 1998, the estimated incidence of malignancy was similarly low (1.6%) 23 . If, however, thyroid tissue is found in the lateral cervical lymph nodes, a metastasis of a malignant thyroid tumor should be excluded.…”

Section: Discussionmentioning

confidence: 95%

Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter. Brief literature review

Kousta

Konstantinidis²,

Michalakis³

et al. 2005

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Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter is a rare entity. We present a 27-year old asymptomatic woman with a recent history of a painless mass in the left side of her lower neck. Thyroid function tests were normal. An ultrasound of her neck showed a multinodular goiter and a 3.4 cm solid mass in the left lower cervical area. These findings were confirmed by an MRI scan of her neck. The Tc99m Pertechnetate scan showed the presence of a functioning area under the left lobe of the thyroid gland. The patient underwent surgery. The cervical mass was identified as a structure separate from the left lobe of the thyroid, without any attachments to the body of the gland and was uniformly resected. A subtotal thyroidectomy was also performed. The histology revealed that the separate structure represented ectopic thyroid tissue. The patient had an uneventful postoperative recovery, subsequent to which she was euthyroid and had normal calcium levels.

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Section: Discussionmentioning

confidence: 95%

Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter. Brief literature review

Kousta

Konstantinidis²,

Michalakis³

et al. 2005

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“…EITT was first described by Ziemssen in 1875 (reference # 59 cited by Dowling [14]). Since then, at least 130 additional cases have been described (13,14,(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42)(43)(44)(45)(46). Most cases have been reported from the endemic goiter regions of the world and Europe (14,31).…”

Section: Discussionmentioning

confidence: 99%

“…Certainly there are cases where a diagnosis of thyroid cancer has later been reversed or disputed (41,42). Two recent cases of malignancy (37) or possible malignancy (39) have been reported with EITT. Authors of a recent review of 14 cases of EITT considered only 2 cases of thyroid cancer within EITT to be well documented, giving a 14% incidence of malignancy (28).…”

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confidence: 99%

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Ectopic Intratracheal Thyroid: An Illustrative Case Report and Literature Review

Bowen-Wright

Jonklaas

2005

Thyroid

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A 19-year-old woman was treated with bronchodilators for new-onset dyspnea with exercise. Her symptoms progressively worsened, culminating 4 months later in acute shortness of breath at rest. Flow-volume loops suggested a fixed obstruction and a computed tomography scan of the neck revealed a large subglottic mass. The patient underwent emergent tracheostomy and laryngoscopy and a near-obstructing intratracheal mass was found. Biopsy showed ectopic thyroid tissue. Magnetic resonance imaging of the neck showed a 1.4-cm tracheal lesion and a normally located thyroid gland. The intratracheal mass was resected endoscopically. Pathology revealed hyperplastic ectopic thyroid tissue. The patient has been maintained on thyroid hormone suppression therapy for 2 years without growth of the residual intratracheal thyroid tissue. She recently underwent a surgical palate expansion. We present this case, along with a literature review of ectopic intratracheal thyroid, its epidemiology, possible etiologies, genetic underpinnings, presentation, and treatment. The co-occurrence of an ectopic thyroid, a functioning orthotopic gland, and a high arched palate is also discussed.

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“…It can be a true ectopic intralaryngotracheal thyroid with no connection with the main thyroid gland (Waggoner, 1958), or a false aberrant intralaryngotracheal thyroid connected to the main gland through a defect in the laryngeal or tracheal cartilages (Waggoner, 1958), intraluminal invasion of the larynx or trachea by frank carcinoma can occur. Malignant transformation of the ectopic intralaryngotracheal thyroid is rare [3].…”

Section: Discussionmentioning

confidence: 99%

Primary Ectopic Papillary Carcinoma of Thyroid in the Larynx: An Unusual Presentation

Menon

Balakrishnan

Valliathan

2018

Asian J Pharm Clin Res

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Ectopic thyroid is the result of the failure of migration of thyroid along its tract from the floor of the primitive foregut to its final pretracheal position. The incidence of an ectopic lesion in adults is 7%. Most common location is the base of tongue (lingual). Other diverse sites are larynx, trachea, mediastinum, and pericardium. These ectopic tissues may develop the same diseases as the thyroid gland. Here, we report a case of a young female presenting with a foreign body sensation in the throat and on examination revealed a smooth submucosal swelling involving the supraglottis. The entire cyst was excised in toto by KTP 532 laser via an endolaryngeal approach and it was reported as papillary carcinoma of the thyroid. Literature search reported only a few cases of intralaryngeal ectopic thyroid and none with a papillary carcinoma of the larynx. This is the first reported case of papillary carcinoma of thyroid in the larynx.

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Intralaryngotracheal thyroid – ectopic thyroid or invasive carcinoma?

Cited by 24 publications

References 16 publications

Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter. Brief literature review

Ectopic thyroid tissue in the lower neck with a coexisting normally located multinodular goiter. Brief literature review

Ectopic Intratracheal Thyroid: An Illustrative Case Report and Literature Review

Primary Ectopic Papillary Carcinoma of Thyroid in the Larynx: An Unusual Presentation

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