Intrahepatic rupture of a caudate lobe adenoma in liver adenomatosis

Abstract

Hepatic adenomatosis is a rare benign disease that is more common in young and middle-aged women who are non-steroid dependent; it is usually symptomatic, progressive, and susceptible to hemorrhagic complications. Malignant transformation within adenomas is rare. The management of hepatic adenomatosis remains difficult due to the absence of predictive signs of complications, other than the size of the adenomas. Resective surgery is usually indicated, but liver transplantation could be an indication in highly symptomatic or progressive forms of the disease and represents the treatment of choice in cases of malignant transformation. We report a case of intrahepatic rupture of a caudate lobe adenoma which occurred in an adolescent with hepatic adenomatosis; we also present a brief review of the literature.

Liver adenomatosis: re‐evaluation of aetiology and management

“…Furthermore, clinical status, laboratory and radiological evaluation, histopathology, surgical management and outcome were reviewed. All published case reports and series were reviewed and key features were analysed in detail (1–4, 5, 7–9, 11–42). A search in the medical databases Medline (1 January 1960–January 2006), Cochrane database of Systemic Reviews, Cochrane Clinical Trial Register and Embase was performed using MESH terms liver adenoma and liver adenomatosis.…”

Surgical Management of Spontaneous Ruptured Hepatocellular Adenoma

“…HA is a rare benign hepatic neoplasm that is of interest for at least three reasons: (1) it may be difficult to distinguish from other benign or malignant hepatic tumors; (2) it may undergo malignant transformation and (3) it has a marked tendency to hemorrhage 18–21. HA is notoriously difficult to diagnose pre-operatively by clinical, radiographic, or histological means.…”