Intragastric Balloon in Association with Lifestyle and/or Pharmacotherapy in the Long-Term Management of Obesity

Abstract

BIB represents an efficacious long-term obesity treatment when supplemental strategies, as lifestyle modifications or pharmacotherapy, are established for weight maintenance after its removal.

Efficacy of intragastric balloon for the management of obesity: experience from Kuwait

“…However, when used in conjunction with pharmacological, dietary, behavioral modification, lifestyle changes, or a combination of these methods, superior results may be produced [12,13].…”

“…The most commonly used example is the bioenterics intragastric balloon (BIB). It is slowly gaining popularity, and a number of studies were carried out with mixed results regarding its efficacy, tolerability, and safety [10][11][12][13].…”

Indications and Limitations of Bariatric Intervention in Severely Obese Children and Adolescents With and Without Nonalcoholic Steatohepatitis

“…The long-term effect of BIB, combined with pharmacotherapy, was superior to the combination with lifestyle modification only (84,85). Some patients were reported to continue losing weight for up to 22 months of follow-up after balloon extraction (86).…”

The REDUCE pivotal trial: a prospective, randomized controlled pivotal trial of a dual intragastric balloon for the treatment of obesity

“…Large recent clinical series show weight loss exceeding 40%EWL [8][9][10], as well as multiyear follow-up showing maintenance of weight loss [11]. Intragastric balloons have been used sequentially resulting in augmented weight loss [7,9,[12][13][14], as well as with weight loss drugs for greater loss or improved postimplant weight loss maintenance [15][16]. Modern balloons have an acceptable safety profile but can be associated with initial accommodative symptoms, reflux and gastric ulcers; serious complications are rare and include periprocedural gastrointestinal tract perforation, and intestinal obstruction arising from balloon deflation and migration out of the stomach [1][2]11,[17][18][19][20][21][22].…”