Intraerythrocytic development and antigenicity of Plasmodium falciparum and comparison with simian and rodent malaria parasites

Membrane structure and function of malaria parasites and the infected erythrocyte

“…A similar protein was found in P. knowlesi (Boyle, Newbold, Wilson & Brown, 19836). Falanga, de Silveira & Pereira da Silva (1982) also carried out studies with P. chabaudi and were able to identify stage-specific proteins using [ 35 S]methionine incorporation.…”

“…The M T 250 K protein, synthesized late in the intra-erythrocytic development cycle, was found not to be present in ring stages after merozoite invasion, suggesting it to be a component of the invading merozoite, possibly of the coat (Boyle, March, Newbold & Brown, 1983a). A similar protein was found in P. knowlesi (Boyle, Newbold, Wilson & Brown, 19836). Falanga, de Silveira & Pereira da Silva (1982) also carried out studies with P. chabaudi and were able to identify stage-specific proteins using [ 35 S]methionine incorporation.…”

“…The M T 150 K protein was not lost upon merozoite invasion, whereas the 200 K protein was. Since antibodies to the 200 K protein bind to undisrupted mature trophozoite-and schizont-infected red cells it was suggested that this protein could play a role in erythrophagocytosis prior to merozoite release (Boyle et al 19836). Lorand, Hawkins, Michalska & Perkins (1984) studied P. falciparum-iniected erythrocytes labelled with [ 35 S]methionine and found that (after crossed-immunoelectrophoresis) significant amounts of radioactivity were immunoprecipitated by antisera specific for spectrin, band 3 and glycophorin.…”