Intradural extramedullary spinal spread of oligoastrocytoma

Huang, James Guoxian; Kavar, Bhadrakant; Smith, Paul D.

doi:10.1016/j.jocn.2006.06.012

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…11 The metastatic potential of pilocytic astrocytomas 5,9,18 and oligoastrocytomas 16,33 has also been described. Metastasis by a low-grade, nonpilocytic astrocytoma has been rarely reported in the literature, although the first report was in 1930.…”

Section: Discussionmentioning

confidence: 99%

Endoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination

Margetis¹,

Rajappa²,

Cope

et al. 2015

PED

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A 21-year-old man presented with triventricular hydrocephalus due to a tectal mass. He underwent an endoscopic third ventriculostomy, and multiple nodules were identified at the floor of the third ventricle intraoperatively. Surgical pathology of one of these lesions demonstrated that the tissue represented a low-grade astrocytoma. The case highlights the existing potential of neuroendoscopy to reveal neuroimaging-occult lesions, in spite of the significant advances of MRI. Furthermore, the combination of the age of the patient, the nonenhancing MRI appearance, and the multifocality of the lesions constitutes a rare and interesting neoplastic presentation within the brain. The constellation of findings likely represents dissemination of a low-grade tectal glioma via the CSF compartment.

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Section: Discussionmentioning

confidence: 99%

Endoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination

Margetis¹,

Rajappa²,

Cope

et al. 2015

PED

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“…Symptoms of metastatic spinal localization occur in almost all reported cases after the treatment of brain glioma, 8–11 even many years after diagnosis. 12,13 On the other hand, onset with symptoms of a spinal metastasis is a very rare event in patients with unknown brain glioma.…”

Section: Introductionmentioning

confidence: 99%

Brain gliomas presenting with symptoms of spinal cord metastasis

Mariniello¹,

Peca²,

De³

et al. 2015

Neuroradiol J

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Three patients with brain gliomas (aged 41, 37, and 43 years) presented spinal cord symptoms as first neurological presentation (two cases) or at anaplastic progression (one case). Histologically, two cases were anaplastic (WHO III) astrocytomas and one anaplastic (WHO III) oligodendroglioma. The spinal surgery consisted of partial tumor resection in two cases with localized spinal cord metastasis, and tumor biopsy in another with diffuse spreading to the conus and cauda. Spinal irradiation was performed in one case. The time interval between the spinal surgery and the appearance of brain symptoms was very short (1 month or less). Two patients underwent brain surgery (tumor resection in one and stereotactic biopsy in another). The survival time was very short (2 and 3 months) in the two patients with anaplastic astrocytoma, whereas the patient with anaplastic oligodendroglioma survived 1 year after the spinal surgery. Brain gliomas may exceptionally present with symptoms of a spinal cord metastasis. The magnetic resonance imaging finding of a spinal cord enhancing lesion, particularly if associated with root enhancement, should suggest the presence of a brain glioma. In cases with a localized spinal lesion, an early spinal surgery is advised for both diagnosis and decompression of the nervous structures. However, the clinical outcome is poor and the survival time is short.

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Comment on “A report of the natural history of leptomeningeal gliomatosis”

Cher

2011

Journal of Clinical Neuroscience

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Intradural extramedullary spinal spread of oligoastrocytoma

Cited by 4 publications

References 14 publications

Endoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination

Endoscopic diagnosis of an MRI-occult, low-grade glioma with ependymal dissemination

Brain gliomas presenting with symptoms of spinal cord metastasis

Comment on “A report of the natural history of leptomeningeal gliomatosis”

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