Intradural dirofilariasis mimicking a Langerhans cell histiocytosis tumor

Perret-Court, Audrey; Coulibaly, Boubacar; Ranque, Stéphane; Bouvier, Corinne; Léna, G.; Coze, Carole; Verschuur, Arnauld

doi:10.1002/pbc.22114

Cited by 19 publications

(4 citation statements)

References 8 publications

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“…In Asia, the highest levels of infection have been reported in Japan. This nematode is known as most important parasitic infection of dogs in Japan (Perret-Court et al 2009 ).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of dirofilariasis in shepherd and stray dogs in Iranshahr, southeast of Iran

et al. 2019

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Dirofilariasis is a zoonotic parasitic disease, which its cause Dirofilaria immitis , a nematode transmitted by insects and a worldwide dissemination. Dogs and cats are the main hosts of this parasite. Therefore, this study was conducted to determine the prevalence of D. immitis in shepherd and stray dogs in Iranshahr city, southeast of Iran. In this study 49 shepherd dogs and 50 stray dogs selected randomly and the blood samples were taken and sent to parasitology laboratory. Thin and thick thin blood samples were prepared and stained with Giemsa method and modified knott method. The obtained data were analyzed by SPSS 18 statistical software. The overall prevalence of parasite was 30.3%, seven of 49 shepherd dogs (14/3%) and twenty three of 50 stray dogs (46%) were positive. From 30 positive samples, 14.3% of shepherd dogs and 50% of stray dogs were male, and 44.7% of stray dogs were female. 14% of infected shepherd dogs and 38.5% of infected stray dogs were indigenous, and 16.7% of infected shepherd dogs and 72.7% of infected stray dogs were hybrids. There was no statistically significant relationship between the prevalence of D. immitis with age, gender, breed and usage of anti-parasitic drugs. Due to the relatively high contamination of dogs in the city of Iranshahr with this parasite, veterinarians and public health professionals should be considered necessary and preventive measures in relation to this disease.

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“…In Asia, the highest levels of infection have been reported in Japan. This nematode is known as most important parasitic infection of dogs in Japan (Perret-Court et al 2009 ).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of dirofilariasis in shepherd and stray dogs in Iranshahr, southeast of Iran

et al. 2019

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“…The nematodes may also reach deeper body areas, such as lymph nodes [93], the abdominal cavity [93, 99], lungs [1, 56, 158, 246], muscles [247] and even the dura [64].…”

Section: Human Infectionsmentioning

confidence: 99%

Recent advances on Dirofilaria repens in dogs and humans in Europe

et al. 2018

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Dirofilaria repens is a nematode affecting domestic and wild canids, transmitted by several species of mosquitoes. It usually causes a non-pathogenic subcutaneous infection in dogs and is the principal agent of human dirofilariosis in the Old World. In the last decades, D. repens has increased in prevalence in areas where it has already been reported and its distribution range has expanded into new areas of Europe, representing a paradigmatic example of an emergent pathogen. Despite its emergence and zoonotic impact, D. repens has received less attention by scientists compared to Dirofilaria immitis. In this review we report the recent advances of D. repens infection in dogs and humans, and transmission by vectors, and discuss possible factors that influence the spread and increase of this zoonotic parasite in Europe. There is evidence that D. repens has spread faster than D. immitis from the endemic areas of southern Europe to northern Europe. Climate change affecting mosquito vectors and the facilitation of pet travel seem to have contributed to this expansion; however, in the authors’ opinion, the major factor is likely the rate of undiagnosed dogs continuing to perpetuate the life-cycle of D. repens. Many infected dogs remain undetected due to the subclinical nature of the disease, the lack of rapid and reliable diagnostic tools and the poor knowledge and still low awareness of D. repens in non-endemic areas. Improved diagnostic tools are warranted to bring D. repens diagnosis to the state of D. immitis diagnosis, as well as improved screening of imported dogs and promotion of preventative measures among veterinarians and dog owners. For vector-borne diseases involving pets, veterinarians play a significant role in prevention and should be more aware of their responsibility in reducing the impact of the zoonotic agents. In addition, they should enhance multisectorial collaboration with medical entomologists and the public health experts, under the concept and the actions of One Health-One Medicine.Electronic supplementary materialThe online version of this article (10.1186/s13071-018-3205-x) contains supplementary material, which is available to authorized users.

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“…Adult D. immitis reside in the pulmonary arteries and right heart chambers, whereas D. repens is found in subcutaneous tissues (McCall et al, 2008). D. repens is the most important agent of human Dirofilaria infections in Europe, occasionally causing severe or very severe clinical findings, even mimicking tumors (Pampiglione et al, , 2009Pampiglione and Rivasi, 2000;Perret-Court et al, 2009).…”

Section: Introductionmentioning

confidence: 98%