Intraductal papillary mucinous neoplasms of the pancreas: Uncommon imaging presentation, evolution and comparison of guidelines

Minelli, Chiara; Balducci, Federico; Cavalleri, Cristina; Milanetto, Anna Caterina; Ferrara, Francesco; Crimì, Filippo; Quaia, Emilio; Vernuccio, Federica

doi:10.1016/j.ejro.2023.100531

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2024

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“…The first-line modern imaging techniques include contrast-enhanced ultrasound (US), MRI-MRCP and multidetector helical computed tomography, followed by endoscopic US (EUS)[ 8 , 21 , 22 ]. Additionally, EUS may provide guided needle biopsy[ 21 ].…”

Section: To the Editormentioning

confidence: 99%

Current considerations on intraductal papillary neoplasms of the bile duct and pancreatic duct

Pavlidis,

Galanis,

Pavlidis

2024

World J Gastroenterol

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Pancreatobiliary intraductal papillary neoplasms (IPNs) represent precursors of pancreatic cancer or bile duct cholangiocarcinoma that can be detected and treated. Despite advances in diagnostic methods, identifying these premalignant lesions is still challenging for treatment providers. Modern imaging, biomarkers and molecular tests for genomic alterations can be used for diagnosis and follow-up. Surgical intervention in combination with new chemotherapeutic agents is considered the optimal treatment for malignant cases. The balance between the risk of malignancy and any risk of resection guides management policy; therefore, treatment should be individualized based on a meticulous preoperative assessment of high-risk stigmata. IPN of the bile duct is more aggressive; thus, early diagnosis and surgery are crucial. The conservative management of low-risk pancreatic branch-duct lesions is safe and effective.

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Section: To the Editormentioning

confidence: 99%