Intraductal Meibomian Gland Probing in the Management of Ocular Rosacea

Wladis, Edward J.

doi:10.1097/iop.0b013e3182627ebc

Cited by 48 publications

(46 citation statements)

References 5 publications

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“…[202] Similar results were seen by an independent investigator who followed ten patients for a period of 6 months post-probing. [203] These patients have thus far only been assessed using symptom questionnaires, making IVCM-aided quantitative evaluation meibomian gland morphology a necessary next step in validating this promising therapeutic intervention.…”

Section: Diagnostic Imaging In Dry Eye Diseasementioning

confidence: 99%

Image-guided evaluation and monitoring of treatment response in patients with dry eye disease

Qazi

Aggarwal

Hamrah

2014

Graefes Arch Clin Exp Ophthalmol

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Dry eye disease (DED) is one of the most common ocular disorders worldwide. The pathophysiological mechanisms involved in the development of DED are not well understood and thus treating DED has been a significant challenge for ophthalmologists. Most of the currently available diagnostic tests demonstrate low correlation to patient symptoms and have low reproducibility. Recently, sophisticated in vivo imaging modalities have become available for patient care, namely, in vivo confocal microscopy (IVCM) and optical coherence tomography (OCT). These emerging modalities are powerful and non-invasive, allowing real-time visualization of cellular and anatomical structures of the cornea and ocular surface. Here we discuss how, by providing both qualitative and quantitative assessment, these techniques can be used to demonstrate early subclinical disease, grade layer-by-layer severity, and allow monitoring of disease severity by cellular alterations. Imaging-guided stratification of patients may also be possible in conjunction with clinical examination methods. Visualization of subclinical changes and stratification of patients in vivo, allows objective image-guided evaluation of tailored treatment response based on cellular morphological alterations specific to each patient. This image-guided approach to DED may ultimately improve patient outcomes and allow studying the efficacy of novel therapies in clinical trials.

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Section: Diagnostic Imaging In Dry Eye Diseasementioning

confidence: 99%

Image-guided evaluation and monitoring of treatment response in patients with dry eye disease

Qazi

Aggarwal

Hamrah

2014

Graefes Arch Clin Exp Ophthalmol

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“…In limited case series, intraductal probing has been reported to relieve symptoms and improve meibomian secretion quality but is not without risk. 47,48 Ductal and subconjunctival hemorrhage (Fig. 2) with discomfort have been reported, and the need to reprobe for recurrence of symptoms in certain patients is well documented.…”

Section: Meibomian Gland Expressionmentioning

confidence: 96%

“…47 Benefits include improvement in OSDI scores, less reliance on doxycycline, and, in many cases, lasting relief of symptoms with less long-term artificial tear usage. 48 …”

Section: Meibomian Gland Expressionmentioning

confidence: 97%

Ophthalmic Procedures for Treatment of Advanced Ocular Surface Diseases

Bartlett¹,

Bartlett²

2015

Optometry and Vision Science

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Dry eye disease and other ocular surface diseases are complex multifactorial disorders often characterized by ocular surface inflammatory changes, instability of the tear film, and functional vision impairment. Recent research has led to new concepts regarding diagnosis and management, and therapeutic interventions now include ocular lubricants, secretagogues, topical and systemic anti-inflammatory and immunosuppressive agents, tear preservation, and, for advanced cases, a variety of surgical approaches. This review considers contemporary procedures for treatment of advanced ocular surface diseases, including thermal and electrocautery of the lacrimal puncta, lid surgeries such as tarsorrhaphy, and multiple procedures to protect the exposed or compromised ocular surface.

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“…Estos vasos dilatados son más frecuentes en las áreas interpalpebrales de la conjuntiva bulbar, y pueden ser grandes y tortuosos y llevar, a veces, a un diagnóstico erróneo de conjuntivitis infecciosa 7 .…”

Section: Patología Conjuntivalunclassified

“…El tratamiento más eficaz es la tetraciclina sistémica, en dosis de 250 mg cuatro veces al día. El efecto terapéutico de la tetraciclina no está relacionado con su acción antibacteriana; se desconoce por qué la rosácea responde a la tetraciclina 7 .…”

Section: Formas Gravesunclassified

La rosácea ocular en la frontera de la dermatología y la oftalmología

Jacob¹,

Bueis²,

Casas³

2016

Más Dermatol

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La rosácea es una enfermedad cutánea caracterizada por un eritema facial que se localiza en la nariz, las mejillas, la frente y el mentón, y que, con el tiempo, se hace persistente, acompañado de pápulas y pústulas 1 . En algunas ocasiones, se produce hiperplasia de tejidos blandos. Es una enfermedad muy común. Es más frecuente en personas de piel clara, durante la juventud y la madurez. Se observa un predominio del sexo femenino, aunque el desarrollo de hiperplasia de tejidos blandos de la nariz o rinofima es más común en hombres. ETIOpATOGENIALa etiología se desconoce, pero se han identificado varios factores que contribuyen a su desarrollo como: predisposición genética, trastornos psicológicos, parasitación por el ácaro Demodex folliculorum y alteraciones digestivas inespecíficas o relacionadas con Helicobacter pylori. Ninguno de ellos se ha confirmado de forma definitiva. Los pacientes presentan labilidad vasomotora o hiperreactividad vascular facial con tendencia a la vasodilatación ante varios estímulos como el calor, el frío, las radiaciones solares, las bebidas alcohólicas, las comidas calientes o las emociones. Son frecuentes los episodios de rubor. INTRODUCCIÓN: IMpORTANCIA DE LA COLAbORACIÓN MULTIDIsCIpLINARIALa rosácea es una enfermedad multidisciplinaria, que obliga, en muchas ocasiones, a la colaboración entre dos especialidades que tienen muchas afinidades entre sí, como son la dermatología y la oftalmología.

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Intraductal Meibomian Gland Probing in the Management of Ocular Rosacea

Cited by 48 publications

References 5 publications

Image-guided evaluation and monitoring of treatment response in patients with dry eye disease

Image-guided evaluation and monitoring of treatment response in patients with dry eye disease

Ophthalmic Procedures for Treatment of Advanced Ocular Surface Diseases

La rosácea ocular en la frontera de la dermatología y la oftalmología

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