Intraductal breast masses: Sonographic and mammographic predictors of malignancy

Sheikh, Hesham El; Almetaher, Hesham Almohamady; Abdalla, Hamdy S.; Shareef, Mohamed

doi:10.1016/j.ejrnm.2015.06.020

Cited by 7 publications

(10 citation statements)

References 13 publications

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“…According to Hesham and Almohamady, malignancy is more common if an Intraductal mass fills the duct and extends outside the duct with a distance from the nipple more than 1.5 cm. In our case also the mass was filling the duct as well as extending outside the duct and was 1.8 cm away from the nipple thus favoring the malignant nature of the mass [9]. Ultrasound and MRI can help in making a diagnosis of Invasive Papillary Carcinoma of the breast.…”

Section: Discussionmentioning

confidence: 50%

Invasive papillary carcinoma of the breast: a rare case report

Issar¹,

Ravindranath²,

Dewangan³

2021

Egypt J Radiol Nucl Med

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Background Invasive Papillary Carcinomas (IPC) are rare and account for approximately 0.5% of all invasive breast carcinomas. Most of them are seen in post-menopausal women and have a good prognosis. These tumors lack the myoepithelial cell layer (MCL) within the papillae or at the periphery of the tumor with areas showing stromal invasion or invasion into lymphovascular spaces. Immunohistochemistry (IHC) for myoepithelial cells and basement membrane is essential for the diagnosis of invasive cancer. Case presentation We present a rare case of IPC in a 74-year-old woman who presented with complaints of gradually increasing painless retroaerolar mass in the left breast of two months duration. The mass was irregular, having an oblong as well an adjacent high density mass lesion on mammography. Ultrasound (US), and Magnetic Resonance Imaging (MRI) helped in the diagnosis of the possibility of a malignant breast lesion. Left-sided modified radical mastectomy was performed and the specimen was histopathologically diagnosed as Invasive Papillary carcinoma. Immunohistochemistry confirmed the diagnosis. Conclusions Invasive Papillary Carcinomas of the breast are rare cancers in post-menopausal women. We have highlighted the role of Mammography, US, and MRI in early diagnosis so that timely management is possible.

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Section: Discussionmentioning

confidence: 50%

Invasive papillary carcinoma of the breast: a rare case report

Issar¹,

Ravindranath²,

Dewangan³

2021

Egypt J Radiol Nucl Med

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“…DtP has been known for a long time to be associated with malignancy. DtP >15 mm on mammography and ultrasound implies that the lesion is probably malignant 36. On the other hand, this feature has not been associated with malignancy for shear wave elastography,37 and there is no literature available regarding DtP in CEUS.…”

Section: Discussionmentioning

confidence: 99%

“…DtP >15 mm on mammography and ultrasound implies that the lesion is probably malignant. 36 On the other hand, this feature has not been associated with malignancy for shear wave elastography, 37 and there is no literature available regarding DtP in CEUS. In the present study, DtP of malignant lesions (true positive and false negative) was larger than for benign lesions.…”

Section: Discussionmentioning

confidence: 99%

<p>A multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions</p>

Tang

Chen

et al. 2019

CMAR

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PurposeTo evaluate a classification model of contrast-enhanced ultrasound (CEUS) and examine the characteristics of patients with false-negative diagnosis.Patients and methodsA retrospective secondary analysis of a multicenter trial of CEUS for breast cancer diagnosis (from August 2015 to April 2017) was undertaken. Patients (n=1,023) with Breast Imaging Reporting and Data System 4–5 lesions on B-mode ultrasound underwent CEUS. Pathological diagnoses were available from surgical or biopsy specimens for correlation. Lesion maximum diameter (LMD), distance to the papilla (DtP), distance from the superficial edge of the lesion to the skin (DtS), distance from the deep edge of the lesion to the pectoralis muscle (DtPM), and body mass index (BMI) were evaluated.ResultsMedian age and BMI were 48.0 and 41.2 years and 23.2 and 22.4 kg/m2 for patients with malignant and benign lesions, respectively. Overall sensitivity, specificity, and accuracy of CEUS for malignancy were 89.4%, 65.3%, and 75.8%, respectively. The patients with true-positive and false-negative diagnosis (ie, with malignant lesion) were older than those with false-positive and true-negative diagnosis (ie, with benign lesion). Patients with true-positive and false-positive diagnoses had higher BMI than patients with true-negative and false-negative diagnoses (P=0.004). Patients with true-positive and false-negative diagnoses had larger LMD and DtP, as well as smaller DtS and DtPM.ConclusionOlder age, higher BMI, larger LMD and DtP, and smaller DtS and DtPM were associated with malignant lesions on CEUS. Patients with these characteristics should undergo further imaging.

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“…These ductal carcinomas are usually close to the subareolar region but can be found elsewhere. The patient may feel a small painless lump or be aware of a clear or bloody discharge from the nipple [2].…”

Section: Introductionmentioning

confidence: 99%

Doppler Indıces Evaluatıon In Malıgnant Breast Lesıons: A Revıew

Jain

Phatak

Dhande

et al. 2021

JPRI

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The incidence of breast malignancy has displayed a rapid rise in recent times. It is one of the most common malignancies found in women. Women should be educated and made aware about self breast examination in order to detect malignancies at an early stage so that the prognosis can be improved. Breast pathologies can be classified into malignant and benign ones on the basis of signs and symptoms and by ultrasonography but can be confirmed on histopathology which remains the gold standard. Breast ultrasonography is the most common non ionizing radiological investigation used to assess breast lesions especially in women with dense or painful breasts. Breast carcinomas appear irregularly shaped hypoechoic lesions with non-circumscribed margins, but these features can rarely be manifested by benign lesions as well. Recent introduction of doppler ultrasound has led to an increase in the sensitivity of detecting breast carcinoma since most of the breast malignancies are hyper vascular and they show high resistivity index on spectral analysis. Angiogenesis in malignant lesions lead to formation of structurally abnormal and tortuous vessels with increased resistive index. Several studies on doppler analysis of breast malignancies have shown Doppler ultrasound to be a safe and effective modality showing acceptable diagnostic accuracy for non-invasive characterization of malignant breast lesions. Therefore, it can be employed as an alternative to histopathology in patients who present with breast lesions.

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Intraductal breast masses: Sonographic and mammographic predictors of malignancy

Cited by 7 publications

References 13 publications

Invasive papillary carcinoma of the breast: a rare case report

Invasive papillary carcinoma of the breast: a rare case report

<p>A multicenter study of a contrast-enhanced ultrasound diagnostic classification of breast lesions</p>

Doppler Indıces Evaluatıon In Malıgnant Breast Lesıons: A Revıew

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