Intradiploic epidermoid tumors (cholesteatoma of the skull)

Adelstein, Leo J.

doi:10.1016/0002-9610(49)90207-x

Cited by 7 publications

(1 citation statement)

References 6 publications

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“…Intradiplopic orbital dermoid and epidermoid cysts are rare, benign tumors, with only 49 cases reported in the literature. [ 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 ] Orbital dermoid cysts are far more common and are most often periocular, with several large series reporting over 80% presenting as a subcutaneous mass. [ 1 52 ] Deep orbital dermoid cysts, also referred to as endophytic cysts, have also been reported, and are more often present later in life with orbital inflammation.…”

Section: Discussionmentioning

confidence: 99%

Differentiating intradiploic orbital dermoid and epidermoid cysts utilizing clinical features and machine learning

Tooley

Tailor²,

Tran³

et al. 2022

Indian Journal of Ophthalmology

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Purpose: The purpose of this study was to characterize intradiploic dermoid and epidermoid orbital cysts to determine any differences in clinical, radiographic, or surgical features. Methods: A retrospective review was performed of patients presenting with intradiplopic dermoid or epidermoid cysts. Additionally, a complete review of the literature was performed to identify cases of intradiplopic orbital dermoid and epidermoid cysts. Data collected included age, sex, presenting symptoms, location of intradiplopic cyst, ophthalmic findings, treatment, and follow-up. Clinical features of dermoid versus epidermoid cyst were compared. Additionally, machine-learning algorithms were developed to predict histopathology based on clinical features. Results: There were 55 cases of orbital intradiploic cysts, 49 from literature review and six from our cohort. Approximately 31% had dermoid and 69% had epidermoid histopathology. Average age of patients with dermoid cysts was significantly lesser than that of patients with epidermoid cysts (23 vs. 35 years, respectively; P = 0.048). There was no difference between sex predilection, presenting symptoms, radiographic findings, or surgical treatment of dermoids and epidermoids. The majority of patients (64%) underwent craniotomy for surgical removal. Machine-learning algorithms KStar and Neural Network were able to distinguish dermoid from epidermoid with accuracies of 76.3% and 69%, respectively. Conclusion: Orbital intradiploic cysts are more commonly epidermoid in origin. Dermoid cysts presented in younger patients; however, there were no other significant differences in features including ophthalmic or radiographic findings. Despite similar features, machine learning was able to identify dermoid versus epidermoid with good accuracy. Future studies may examine the role of machine learning for clinical guidance as well as new surgical options for intervention.

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Section: Discussionmentioning

confidence: 99%

Differentiating intradiploic orbital dermoid and epidermoid cysts utilizing clinical features and machine learning

Tooley

Tailor²,

Tran³

et al. 2022

Indian Journal of Ophthalmology

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Supratentorial Tumors Among Children

Miller¹

1952

Arch NeurPsych

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TUMORS above the tentorium cerebelli occur among children less frequently than do infratentorial tumors,1 the usual ratio of supratentorial to infratentorial tumors being 1: 2.The cases which we wish to report were taken from the records at the Mayo Clinic. Of 4,318 verified brain tumors, 518 occurred among children from birth through 14 years of age. The cases were reviewed as to type and location of tumor; age, sex, and survival of patients, and symptoms, signs, and roentgenologic findings related to the tumors. The pertinent literature also was reviewed. A total of 190 supratentorial tumors were found, 97, or 51.1% of which were recorded as gliomas according to the classification used by Svien, Mabon, Kernohan, and Adson.2 Fifty-eight of these were astrocytomas; 24, ependymomas; 11, oligodendrogliomas, and 4, neuroastrocytomas. Other supratentorial tumors included 35 craniopharyngiomas, 14 tumors of the pineal body, 12 sarcomas, 12 meningiomas, 9 tumors of the pituitary gland, 7 vascular tumors, 3 epidermoid tumors, and 1 tuberculoma. Keith, Craig, and Kernohan,3 in 1949, reported that 84% of 427 verified intracranial tumors occurring among children were gliomas, and Bailey and associates lb reported that 70% of supratentorial tumors in children were gliomas. The cases of astrocytomas, ependymomas, oligodendrogliomas, and neuroastro¬ cytomas (Fig. 1) will be discussed under the common headings of gliomas.

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Erkennung, Differentialdiagnose und Behandlung der Geschwülste und Entzündungen der Schädelknochen einschließlich Orbita

Gerlach¹,

Simon²

1960

Handbuch Der Neurochirurgie

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Intradiploic epidermoid tumors (cholesteatoma of the skull)

Cited by 7 publications

References 6 publications

Differentiating intradiploic orbital dermoid and epidermoid cysts utilizing clinical features and machine learning

Differentiating intradiploic orbital dermoid and epidermoid cysts utilizing clinical features and machine learning

Supratentorial Tumors Among Children

Erkennung, Differentialdiagnose und Behandlung der Geschwülste und Entzündungen der Schädelknochen einschließlich Orbita

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