Intradialytic complications: pathophysiology, prevention and treatment

Sande, Frank M. van der; Levin, Nathan W.; Kooman, Jeroen P.; Hoenich, Nicholas A.; Leunissen, Karel M.L.

doi:10.1007/978-1-4020-2275-3_46

Cited by 2 publications

(1 citation statement)

References 225 publications

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“…Hypotension is related to predialysis blood pressure and IDWG, and occurs primarily due to inability of the body to respond to the rates of fluid and solute removal occurring during treatment. 15 Thus, intensified ultrafiltration increases the risk of hypotensive episodes during dialysis. 12 In that study, the importance of a longer HD duration/session was independently associated with a lower mortality risk.…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular conditions in hemodialysis patients may be worsened by extensive interdialytic weight gain

Holmberg

Stegmayr

2009

Hemodialysis International

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The risk of death is increased for hemodialysis (HD) patients compared with age-matched healthy subjects, the main reason for this being cardiovascular conditions. This prospective study investigated whether the burden of interdialytic weight gain (IDWG) was of importance for cardiovascular end points and survival. A total of 97 HD patients were studied. The end points included death (reasons given), acute myocardial infarction, or coronary vascular intervention. The extent of ultrafiltration was measured at predefined follow-up points. The IDWG was calculated as ultrafiltration/body weight given in weight%. The burden of IDWG was analyzed. End points occurred in 77 (79%) of the patients during the 5-year study period. The extent of IDWG was higher in those with end points due to cardiovascular reasons (3.77 weight% vs. 3.19 P<0.001), cardiac reasons (P<0.001), congestive heart failure (P<0.01), aortic aneurysm, and intracerebral bleeding (P<0.024). To reduce the risk for cardiovascular events, it is important to avoid too extensive IDWG in HD patients.

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Section: Discussionmentioning

confidence: 99%

Cardiovascular conditions in hemodialysis patients may be worsened by extensive interdialytic weight gain

Holmberg

Stegmayr

2009

Hemodialysis International

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Acid-Base and Electrolyte Abnormalities during Renal Support for Acute Kidney Injury: Recognition and Management

Granado

Bouchard²

2012

Blood Purif

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Acute kidney injury (AKI) is associated with electrolyte and acid-base disturbances such as hyperkalemia, metabolic acidosis, hypocalcemia and hyperphosphatemia. The initiation of dialysis in AKI can efficiently treat these complications. The choice of dialysis modality can be made based on their operational characteristics to tailor the therapy according to the clinical scenario. Each dialysis modality can also trigger significant electrolyte and acid-base disorders, such as hypokalemia, hypophosphatemia and metabolic alkalosis, which may direct changes in fluid delivery and composition. Continuous techniques may be particularly useful in these situations as they allow more time for correction and to maintain balance. This review provides an overview of the electrolyte and acid-base disturbances occurring in AKI and after the initiation of dialysis and discusses therapeutic options in this setting.

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Intradialytic complications: pathophysiology, prevention and treatment

Cited by 2 publications

References 225 publications

Cardiovascular conditions in hemodialysis patients may be worsened by extensive interdialytic weight gain

Cardiovascular conditions in hemodialysis patients may be worsened by extensive interdialytic weight gain

Acid-Base and Electrolyte Abnormalities during Renal Support for Acute Kidney Injury: Recognition and Management

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