Intracranial rheumatoid nodules: a rare localization of rheumatoid arthritis

Verboven, Griet; Sluyts, Yasmine; Mulder, Gert De; Stessels, Filip; Cauwer, Harald De

doi:10.1007/s13760-023-02200-6

Cited by 1 publication

(2 citation statements)

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“…20 Rheumatoid nodules can be seen on pathological examination of the biopsies of patients ultimately diagnosed with rheumatoid meningitis or CNS vasculitis but have also been reported to occur as mass lesions in the parenchyma. 21,22 Rheumatoid nodules presenting as isolated mass lesions are exceedingly uncommon. In most reported cases of RA with CNS vasculitis and rheumatoid nodules presenting as mass lesions, there is associated meningeal involvement as well.…”

Section: Key Pointsmentioning

confidence: 99%

“…In a review of cases of CNS rheumatoid vasculitis, most patients in whom testing results were reported had elevations in serum biomarkers of RA 20 . Rheumatoid nodules can be seen on pathological examination of the biopsies of patients ultimately diagnosed with rheumatoid meningitis or CNS vasculitis but have also been reported to occur as mass lesions in the parenchyma 21,22 . Rheumatoid nodules presenting as isolated mass lesions are exceedingly uncommon.…”

Section: Neurologic Manifestations Of Select Systemic Autoimmune Dise...mentioning

confidence: 99%

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Neurologic Manifestations of Rheumatologic Disorders

McCombe

2024

CONTINUUM: Lifelong Learning in Neurology

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OBJECTIVE This article provides an overview of the neurologic manifestations of sarcoidosis and select rheumatologic disorders. An approach to the assessment and differential diagnosis of characteristic clinical presentations, including meningitis and vasculitis, is also reviewed. A review of treatment options is included as well as discussion of distinct areas of overlap, including rheumatologic disease in the setting of neuromyelitis spectrum disorder and demyelinating disease in the setting of tumor necrosis factor-α inhibitors. LATEST DEVELOPMENTS An increased understanding of the immune mechanisms involved in sarcoidosis and rheumatologic diseases has resulted in a greater diversity of therapeutic options for their treatment. Evidence directing the treatment of the central nervous system (CNS) manifestations of these same diseases is lacking, with a paucity of controlled trials. ESSENTIAL POINTS It is important to have a basic knowledge of the common CNS manifestations of rheumatologic diseases and sarcoidosis so that they can be recognized when encountered. In the context of many systemic inflammatory diseases, including systemic lupus erythematosus, IgG4-related disease, and sarcoidosis, CNS disease may be a presenting feature or occur without systemic manifestations of the disease, making familiarity with these diseases even more important.

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Section: Key Pointsmentioning

confidence: 99%

Section: Neurologic Manifestations Of Select Systemic Autoimmune Dise...mentioning

confidence: 99%