Intracranial neoplasms in children in Ibadan, Nigeria

Aghadiuno, P. U.; Adeloye, A; Olumide, A. A.; Nottidge, Vidal A.

doi:10.1007/bf00706729

Cited by 23 publications

(11 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This agrees with the findings of Aghadiuno et al (12) in children and of Jackson and Okubadejo (13) in adults.…”

Section: Discussionsupporting

confidence: 93%

“…Burkitt's lymphoma is a neoplasm primarily involving the jaw and abdomen of African children and is unusual in Caucasians(11). The higher incidence found in this study when compared to 10% found in a previous study (12) may reflect the present socio-economic climate in the country with the prohibitive cost of treatment, and therefore progression of the disease with brain involvement. Involvement of the brain is usually associated with widespread organ involvement and has a poor prognosis (11).…”

Section: Discussioncontrasting

confidence: 67%

“…Craniopharyngiomas accounted for 9.1% of the total which is twice the relative incidence of 4.6% recorded in the series of Cushing (1). Craniopharyngiomas are more common in African children than American children (12,19).…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Intracranial neoplasmin Ibadan, Nigeria

Bj¹,

Shokunbi²,

Pu³

2009

E Af Med Jrnl

View full text Add to dashboard Cite

Objective: To determine the pattern of histopathological variants of intracranial neoplasms, relative distribution of the variants in the age groups and also to determine the gender differences that exist in these tumours. Design: Case control study. Setting: Department of Pathology, University College Hospital, Ibadan, Nigeria. Patients: Two hundred and ten histologically confirmed cases of intracranial neoplasms seen during eleven-year period (1980 to 1990) were analysed. Interventions: Slides of tumours stained with haematoxylin and eosin, reticulin and phosphotungstic acid haematoxylin. Results: Two hundred and ten intracronial neoplasms comprising 172 primary and 48 secondary neoplasms were seen. One hundred and thirty five neoplasms occurred in adults and 75 in children. There was no gender difference, the ratio being 1:1. Gliomas accounted for the largest group of tumours followed by metastases to the brain. Of the gliomas, astrocytoma was the commonest. Craniopharyngiomas were found to be common in children. Germ cell tumours were found to be uncommon. Conclusion: Gliomas are the commonest group of intracranial neoplasms in both adults and children. This is followed by metastatic tumours. Tumours of the sella turcica are predominantly found in children. Involvement of the brain in disseminated Burkitt's lymphomas is predominantly found in Africans as the Burkitt's tumour is uncommon in non Africans.

show abstract

“…This agrees with the findings of Aghadiuno et al (12) in children and of Jackson and Okubadejo (13) in adults.…”

Section: Discussionsupporting

confidence: 93%

Section: Discussioncontrasting

confidence: 67%

See 1 more Smart Citation

Intracranial neoplasmin Ibadan, Nigeria

Bj¹,

Shokunbi²,

Pu³

2009

E Af Med Jrnl

View full text Add to dashboard Cite

show abstract

“…Previous reports suggest that craniopharyngiomas occur more frequently in children aged 5–14 years with a higher incidence in Asia and Africa [4,23,24,25]. Most of the investigations have stated that craniopharyngiomas rank next to medulloblastomas in their incidence rate [3,4,5, 10,14,15,16,17,18,19,20,21,22,23].…”

Section: Discussionmentioning

confidence: 99%

“…In different epidemiological investigations, the upper age limit of childhood varied from 14 to 17 years [3,4,5,14,15,16,17,18,19,20,21,22,23] and even to 21 years [2]; therefore, there may be statistical variation. For a detailed comparison with minor bias, we analyzed the data for the 0–14 and 0–17 age group separately.…”

Section: Discussionmentioning

confidence: 99%

Epidemiology of Nervous System Tumors in Children: A Survey of 1,485 Cases in Beijing Tiantan Hospital from 2001 to 2005

et al. 2008

View full text Add to dashboard Cite

Objective: The purpose of the present retrospective study was to describe the epidemiology of nervous system tumors in children based on the clinical data obtained from a neurosurgical center in Beijing. Patients and Methods: During a 5-year period, from January 2001 to December 2005, 1,485 primary brain and spinal tumors in children up to 17 years of age were diagnosed histopathologically according to the World Health Organization 2000 nervous system tumor classification. The sex predilection, tumor location, and histological grade in relation to age were investigated, and the epidemiological characteristics of the 5 most common brain tumors are discussed. Result: Of the 1,485 cases evaluated, brain and spinal tumors comprised 92.3% (1,371) and 7.7% (114), respectively, with a predominance of low-grade tumors (65.1 and 78.9% for brain and spinal cord, respectively). For all tumors, the overall sex ratio (male to female) was 1.6:1. 61.9% of the brain tumors were supratentorial, whereas an infratentorial location was slightly more common in the 872 brain tumors of neuroepithelial tissue (53.7%). The 5 most common brain tumors were astrocytic tumors (30.5%), craniopharyngiomas (18.4%), medulloblastomas (14.6%), germ cell tumors (GCTs, 7.9%) and ependymal tumors (5.6%). The highest preponderance of boys was observed in GCTs followed by medulloblastomas. The most common types of spinal tumors were ependymal tumors (19.3%), neurilemmomas (16.7%) and astrocytomas (14.9%). Conclusions: Based on a large hospital series of pediatric patients, the present survey revealed the histopathological diversity of childhood neurological neoplasms, and provides a reliable profile of the epidemiology of nervous system tumors in children in a developing country.

show abstract