Intracranial multiple myeloma involving the dura

Tsang, Chi-Sum; Ho, Luen-Cheung; Tan, Tze-Ching

doi:10.1016/j.jocn.2005.02.008

Cited by 8 publications

(9 citation statements)

References 4 publications

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“…It appeared similar to meningioma; in addition, the lesion showed an enhanced line dividing the mass in half which was thought to be a blood supply to the meningioma. Plasmacytoma can be mistaken with meningioma since it has typical radiological features as an extra-axial mass with broad attachment to the dura, hyperdense on CT, isointense with grey matter on T1-weighted MRI, more variable signal intensity on T2-weighted MRI, and strongly and homogeneously enhancing with contrast [2,4,11,13,26]. During operation, it was revealed that the mass was located extra- and intradural, and that enhanced line in the middle of the lesion was actually the dura itself.…”

Section: Discussionmentioning

confidence: 99%

Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma

Rahmah¹,

Brotoarianto²,

Andor³

et al. 2009

Biomed. Imaging Interv. J.

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Intracranial involvement in multiple myeloma (MM) is rarely found, especially with dural involvement. There are only a few cases found concerning MM with intracranial involvement. MM usually involves an older group of patients. Cases involving young patients are very rare. The differential diagnosis of a dural plasmacytoma includes meningioma, metastasis, lymphoma and sarcoma of the dura mater. We present a young patient, 33 years old, with MM presenting an intracerebral mass mimicking meningioma on MRI. MM was diagnosed the previous year. The patient presented with headache, balance disturbance and back pain. MRI revealed an occipital extra-axial mass with a dural tail. Histopathological examination after excision showed MM. Published literatures on intracranial involvement of MM are also discussed. Plasmacytoma should be considered in the differential diagnosis of a solitary dural mass, particularly in a patient with MM.

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Section: Discussionmentioning

confidence: 99%

Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma

Rahmah¹,

Brotoarianto²,

Andor³

et al. 2009

Biomed. Imaging Interv. J.

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“…1 Cranial multiple myeloma may be asymptomatic or present with symptoms and signs of raised intracranial, cranial nerve palsies, proptosis, motor deficit, cognitive changes or seizures. 2 Treatment options include chemotherapy with surveillance, surgical resection with adjuvant radiotherapy, or radiotherapy alone. 3 Although the prognosis for patients with intracranial multiple myeloma is poor, long term survival of up to 25 years following surgical resection and adjuvant radiotherapy has been reported.…”

Section: Discussionmentioning

confidence: 99%

An unusual cause of skull and cervical spine mass lesions

Liubinas

Morokoff

2011

Journal of Clinical Neuroscience

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“…Stwierdzenie zmian nie daje jednak pewnego rozpoznania, wyniki mogą być zarówno pozytywnie, jak i negatywnie fałszywe [11]. Na przykład zmiany w obrębie opon mogą sugerować krwiaki [12,13]. Tomografia komputerowa jest mało czuła w zakresie wykrywania zmian szpiczakowych w OUN.…”

Section: Diagnostykaunclassified

“…Sytuacja ta wiązana jest przez autorów kilku analiz, również tych, którzy nie stwierdzili wyraźnej korelacji białaczki plazmocytowej z zajęciem OUN [6,19], z większym ryzykiem zajęcia OUN. Częstość nacieków w czaszce sąsiadujących z zajętymi w OUN strukturami sprawia, że bierze się pod uwagę możliwość naciekania struktur OUN przez ciągłość [3,12,15]. Ponieważ u części chorych nie stwierdza się krążących plazmocytów ani zajęcia struktur kostnych głowy, niektórzy autorzy wysuwają inne hipotezy dotyczące mechanizmu rozprzestrzeniania się zmian do OUN.…”

Section: Etiologia I Czynniki Ryzykaunclassified

Zajęcie ośrodkowego układu nerwowego w przebiegu szpiczaka plazmocytowego – opis przypadku i przegląd literatury

Jurczyszyn¹,

Olszewska-Szopa²,

Fornagiel³

et al. 2015

Acta Haematologica Polonica

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a c t a h a e m a t o l o g i c a p o l o n i c a 4 6 ( 2 0 1 5 ) 2 4 2 -2 4 7 i n f o r m a c j e o a r t y k u l e Historia artykułu: Słowa kluczowe: szpiczak ośrodkowy układ nerwowy diagnostyka leczenie Słowa kluczowe: Myeloma Central nervous system Diagnosis Treatment a b s t r a c t In multiple myeloma extramedullary involvement occurs in 13% of patients. Central nervous system (CNS) involvement is extremely rare and comprises 1% of cases. Review of literature shows only limited data on this subject and consists mostly of few case reports. Scarce knowledge about CNS involvement in the course of multiple myeloma makes its diagnosis and treatment very difficult and challenging. The authors describe a clinical case which illustrates the problem from a clinician point of view. Furthermore, we analyzed the available data from literature and summarized the current state of knowledge on diagnosis, potential prognostic factors, treatment and prognosis in CNS myeloma involvement.

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Intracranial multiple myeloma involving the dura

Cited by 8 publications

References 4 publications

Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma

Dural plasmacytoma mimicking meningioma in a young patient with multiple myeloma

An unusual cause of skull and cervical spine mass lesions

Zajęcie ośrodkowego układu nerwowego w przebiegu szpiczaka plazmocytowego – opis przypadku i przegląd literatury

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