Intracranial Hemorrhage Produced by Spontaneous Dissecting Intracranial Aneurysm

Intracranial Fusiform Aneurysms: It's Pathogenesis, Clinical Characteristics and Managements

“…Fusiform aneurysms in this study were found in the anterior circulation in 17 (77%) of the patients and in the posterior circulation in 23%. Dissection has been proposed as the main underlying cause of fusiform aneurysms and most commonly involves the posterior circulation, especially vertebral and basilar arteries 1,3,[5][6][7][8][9][10]15,16,19,20,[24][25][26]32,35) However, typical cases of dissecting aneurysm in the posterior circulation were excluded in this study. Dissecting aneurysms can originate in any regions of the anterior circulation, such as the ICA 1,29) , MCA 2,4,6,10,[13][14][15][16]22,26,30) , the ACA 3,10,[16][17][18]24,27,30,32,35) and rarely in the anterior choroidal artery 21) .…”

“…Rupture of the vasa vasorum by shear forces or by stress on the luminal wall then causes intimal tear and fracture of the internal elastic membrane. This permits bleeding into the arterial wall to form a hematoma 1,6) . If the dissection occurs between the internal elastic lamina and the media, the vessel lumen becomes narrow or occluded with an intramural hematoma and the patients present with ischemic symptoms 1,3,6,13,23,35) .…”

“…This permits bleeding into the arterial wall to form a hematoma 1,6) . If the dissection occurs between the internal elastic lamina and the media, the vessel lumen becomes narrow or occluded with an intramural hematoma and the patients present with ischemic symptoms 1,3,6,13,23,35) . If dissection occurs between the media and adventitia, the aneurysm can rupture and the patient will present with SAH or IC-H 1,3,6,13,23,35) .…”

Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases

“…Strokes in young adults resulting from spontaneous dissection of the cervical segment of the extracranial carotid artery are being reported with increasing frequency [1][2][3][4][5][6][7][8] . Ischemia may result from occlusion of the internal carotid artery (ICA) and distal stump embolization to the distal intra-cranial arteries, and may account for major morbidity and mortality in young stroke victims.…”

“…Ischemia may result from occlusion of the internal carotid artery (ICA) and distal stump embolization to the distal intra-cranial arteries, and may account for major morbidity and mortality in young stroke victims. Anticoagulation has been used for this condition but caution has been advised due to the risk of extending the dissection 5 . The lack of therapeutic options has been a limiting factor for the clinical recovery of stroke victims, until the advent of thrombolytic therapy.…”