Intracranial Efficacy of Pyrotinib and Capecitabine Combination Therapy in HER2-Positive Breast Cancer with Brain Metastases
Congcong Wang,
Jinyu Xiang,
Qingyu Zhang
et al.
Abstract:Aim
Approximately 50% of patients diagnosed with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (BC) are estimated to develop brain metastases (BMs). This study was aimed to assess the intracranial efficacy and survival benefits of pyrotinib and capecitabine combination therapy in the treatment of BMs in patients with HER2-positive BC.
Methods
A total of 56 HER2-positive BC patients with BMs were treated with 400 mg pyrotinib once dail… Show more
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