Intracranial EEG in Episodic Memory Research: Possibilities, Limitations, Results

Abstract

Stereoelectroencephalography (sEEG) and electrocorticography (ECoG) are methods of intracranial (invasive) EEG (iEEG). These methods record alterations of local field potential (LFP) using stereotaxically or subdurally implanted invasive electrodes. Nowadays, these methods are widely used for diagnostics and therapy of various neurological disorders. Moreover, they offer a valuable opportunity for fundamental research of cognitive and sensorimotor processes. Here, we address the possibilities and limitations of iEEG for human episodic memory research and review the main results obtained by this method, delineating the functional role of medial temporal lobes structures, the temporal dynamics of their activation, and the role of different frequency oscillations in local and global processing during episodic memory