Intracranial complications of otitic origin.

Proctor, Conrad

doi:10.1288/00005537-196602000-00008

Cited by 63 publications

(26 citation statements)

References 24 publications

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“…Successful surgery and then the introduction of sulphonamides and penicillins further reduced the mortality of LST to below 30 per cent. 14 The improvement in mortality can also be attributed to a combination of earlier diagnosis and treatment. 13,15,16 There were no deaths in our series of patients with LST.…”

Section: Discussionmentioning

confidence: 99%

Management of lateral sinus thrombosis: update and literature review

2003

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The management of four cases of lateral sinus thrombosis (LST) over a four-year period at the Royal Darwin Hospital is presented in this retrospective review. The patients were aboriginal and presented with otalgia, otorrhoea and sepsis. Two cases had an associated complication of an otitic hydrocephalus and a subperiosteal abscess. Cholesteatoma was found in three cases. Computed tomography (CT) scan confirmed the LST in three cases. Three patients were anaemic and thrombocytopenic. All patients had positive blood cultures. The organisms were predominantly mixed anaerobes and Bacteroides species. Three patients were managed surgically as a two-stage procedure. One patient was managed as a single-stage procedure with a modified radical mastoidectomy. Therapeutic anticoagulation was utilized in one case. There were no deaths. The prognosis of LST is good if treatment is instituted early with broad-spectrum intravenous antibiotics and surgery. The role of clot removal at surgery and the use of anticoagulation are discussed in this paper.

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Section: Discussionmentioning

confidence: 99%

Management of lateral sinus thrombosis: update and literature review

2003

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“…The diagnosis of sigmoid sinus thrombosis has been aided by the use of non invasive imaging, most notably MRI/ MRV or less reliably CT [5]. According to a study by Proctor in 1966, the use of antibiotics in conjunction with surgical intervention has decreased the mortality from 40% to essentially 0 [6]. The use of anticoagulation in the setting of otogenic lateral sinus thrombosis remains controversial [7,8].…”

Section: Introductionmentioning

confidence: 99%

Pediatric otogenic lateral sinus thrombosis recanalization

Neilan

Isaacson

Kutz

et al. 2011

International Journal of Pediatric Otorhinolaryngology

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“…In the preantibiotic era, the incidence of mastoiditis and otogenic intracranial complications was high. Approximately 6% of patients with acute or chronic suppurative otitis media developed intracranial complications, and mortality was greater than 80% 1, 2. With the introduction of sulfonamides, there was a 50% reduction in hospitalization for acute otitis media and an 80% reduction in mastoidectomies in children 3.…”

Section: Introductionmentioning

confidence: 99%

Advanced pediatric mastoiditis with and without intracranial complications

et al. 2009

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Nearly a quarter of pediatric patients with coalescent mastoiditis presented with a simultaneous intracranial complication. There was an increased incidence of anaerobic organisms in patients with intracranial complications compared to those without, indicating the importance of culture and antibiotic coverage appropriate for anaerobes. This series demonstrates the role of aggressive surgical management and close collaboration with the infectious disease service for long-term intravenous antibiotic therapy in treating pediatric patients with advanced mastoiditis.

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Intracranial complications of otitic origin.

Cited by 63 publications

References 24 publications

Management of lateral sinus thrombosis: update and literature review

Management of lateral sinus thrombosis: update and literature review

Pediatric otogenic lateral sinus thrombosis recanalization

Advanced pediatric mastoiditis with and without intracranial complications

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