Intracranial cavernous malformations

Rivera, Peter P.; Willinsky, Robert A.; Porter, P.

doi:10.1016/s1052-5149(02)00060-6

Cited by 70 publications

(42 citation statements)

References 45 publications

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“…12 In accordance with these definitions, our patient did not have any obvious hemorrhage at the time of imaging despite the change in signal intensity on the T1-weighted imaging. New or worsened focal neurological deficits associated with the anatomic location of the CM can occur without any evidence of recent hemorrhage in brain imaging.…”

Section: Discussionsupporting

confidence: 79%

MRI appearance of a cerebral cavernous malformation in the caudate nucleus before and after chorea onset

Kobayashi

Aoyama

Sasaki

et al. 2011

Journal of Clinical Neuroscience

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Section: Discussionsupporting

confidence: 79%

MRI appearance of a cerebral cavernous malformation in the caudate nucleus before and after chorea onset

Kobayashi

Aoyama

Sasaki

et al. 2011

Journal of Clinical Neuroscience

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“…MRI can reveal blood products of varying ages and is the best method for the diagnosis and follow-up of cerebral cavernomas [17,18]. CT can demonstrate hemorrhage, and the lesion may be enhanced by contrast administration.…”

Section: Discussionmentioning

confidence: 99%

Surgical Management of Brain Cavernomas in Children

Alexiou¹,

Mpairamidis²,

Sfakianos³

et al. 2009

Pediatr Neurosurg

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Background: Cavernous hemangiomas are benign vascular hamartomas caused by developmental malformations of the vascular bed. They can be found in 0.3–0.7% of the population, whereas one fourth of these lesions occur in children. Methods: In the present study, we report on 16 cases of cavernomas surgically treated in our institute. From each patient’s file, the age, sex, lesion location, symptoms and follow-up were analyzed. Results: The most commonly presenting symptom was epilepsy. Radiological signs of acute hemorrhage were observed in 3 cases. Three children had multiple cavernomas. The parietal lobe was the most common site of occurrence, whereas only 2 cavernomas were infratentorial. There was no operative mortality. Postoperatively, there was no additional neurological deficit, and all patients gradually improved. In a case of pontine cavernoma, there was a need for reoperation due to rebleeding. Conclusion: With the improvement of microsurgical techniques and modern neuroimaging, nearly all cavernomas can be safely removed. Total resection is associated with patients’ clinical improvement and seizure control.

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“…57,116 Typically, the lesions appear as areas of mixed signal intensity on T1-and T2-weighted images and are surrounded by a peripheral area of hypointensity (representing a hemosiderin ring) on T2-weighted images. 119 According to recent reports, the highly sensitive T2-weighted gradient-echo imaging has become the gold standard MR imaging sequence for visualization of CAs.…”

mentioning

confidence: 99%

Management of incidentally discovered intracranial vascular abnormalities

Chalouhi¹,

Dumont²,

Randazzo³

et al. 2011

FOC

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With the widespread use of brain imaging studies, neurosurgeons have seen a marked increase in the number of incidental intracranial lesions, including vascular abnormalities. Specifically, the detection of incidentally discovered aneurysms, arteriovenous malformations, cavernous angiomas, developmental venous anomalies, and capillary telangiectasias has increased. The best management strategy for most of these lesions is controversial. Treatment options include observation, open surgery, endovascular procedures, and radiosurgery. Multiple factors should be taken into account when discussing treatment indications, including the natural history of the disease and the risk of the treatment. In this article, the authors focus on the natural history of these lesions and the risk of the treatment, and they give recommendations regarding the most appropriate management strategy based on the current evidence in the literature and their experience with intracranial vascular abnormalities.

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Intracranial cavernous malformations

Cited by 70 publications

References 45 publications

MRI appearance of a cerebral cavernous malformation in the caudate nucleus before and after chorea onset

MRI appearance of a cerebral cavernous malformation in the caudate nucleus before and after chorea onset

Surgical Management of Brain Cavernomas in Children

Management of incidentally discovered intracranial vascular abnormalities

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