Intracranial arachnoid cysts in a chimpanzee (Pan troglodytes)

Miyabe‐Nishiwaki, Takako; Kaneko, Takaaki; Sakai, Tomoko; Kaneko, Akihisa; Watanabe, A.; Watanabe, Shohei; Maeda, Norihiko; Kumazaki, Kiyonori; Suzuki, Juri; Fujiwara, Ryo; Makishima, Hideki; Nishimura, Takeshi; Hayashi, Misato; Tomonaga, Masaki; Matsuzawa, Tetsuro; Mikami, Atsushi

doi:10.1007/s10329-013-0384-0

Cited by 7 publications

(5 citation statements)

References 44 publications

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“…There were individual differences, but HR and RR were stable within an individual. Apnea was not seen except in Pendesa who has an arachnoid cyst 18,19 and had had apneas on several previous occasions when anesthesia was maintained with sevoflurane. For the current anesthetic, a planned endotracheal intubation was performed, and when apnea was seen, she was manually ventilated for several minutes and dimorpholamine was administered, following which spontaneous breathing recovered.…”

Section: Resultsmentioning

confidence: 98%

Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Miyabe‐Nishiwaki

Kaneko

Yamanaka

et al. 2021

Sci Rep

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Chimpanzees are genetically and physiologically similar to humans. Several pharmacokinetic models of propofol are available and target controlled infusion (TCI) of propofol is established in humans, but not in chimpanzees. The purpose of this study was to investigate if human pharmacokinetic models can accurately predict propofol plasma concentration (Cp) in chimpanzees and if it is feasible to perform TCI in chimpanzees. Ten chimpanzees were anaesthetized for regular veterinary examinations. Propofol was used as an induction or maintenance agent. Blood samples were collected from a catheter in a cephalic vein at 3–7 time points between 1 and 100 min following the propofol bolus and/or infusion in five chimpanzees, or TCI in six chimpanzees. Cp was measured using high-performance liquid chromatography. The Marsh, Schnider and Eleveld human pharmacokinetic models were used to predict Cp for each case and we examined the predictive performances of these models using the Varvel criteria Median PE and Median APE. Median PE and Median APE for Marsh, Schnider and Eleveld models were within or close to the acceptable range. A human TCI pump was successfully maintained propofol Cp during general anesthesia in six chimpanzees. Human propofol pharmacokinetic models and TCI pumps can be applied in chimpanzees.

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Section: Resultsmentioning

confidence: 98%

Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Miyabe‐Nishiwaki

Kaneko

Yamanaka

et al. 2021

Sci Rep

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“…However, in our study, neither record of feline imaging brain scans presented this condition. There also exists a report case of a chimpanzee with intracranial arachnoid cyst in the occipital convexity (Miyabe-Nishiwaki et al 2014).…”

Section: Discussionmentioning

confidence: 99%

A retrospective study of quadrigeminal arachnoid cysts diagnosed by Magnetic Resonance Imaging and Computed Tomography in 26 dogs

et al. 2018

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Arachnoid cysts are accumulations of cerebrospinal fluid that occur within the arachnoid membrane due to the splitting or duplication of this structure. The aim of this retrospective study is to report the occurrence of this condition in 26 dogs, as well as to describe the findings of computed tomography imaging and magnetic resonance image scans and to correlate these with the clinical signs. A prevalence of the condition was observed in males, predominantly in the small breeds Miniature Pinscher and Shih Tzu, with age raging from 2 months to 9 years. The mainly clinical signs observed in these dogs were seizures and cerebellar ataxia. The study concluded that in 17 dogs the quadrigeminal arachnoid cyst was regarded as an incidental finding, in 6 dogs this condition was regarded as the determinant cause of the clinical signs, and in 3 dogs some clinical signs were associated with arachnoid cyst, but they also presented clinical signs involving others sites of intracranial lesion.

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“…However, only a few veterinary neuroradiology reference files for nonhuman primates are currently available. Some examples are case studies of a lateral ventriculomegaly and a mild hippocampal atrophy in a young marmoset (Sadoun et al, 2015), a subacute necrotizing encephalopathy in a pig-tailed macaque (Bielefeldt-Ohmann et al, 2004), an ependymal cyst in a cynomolgus macaque (Macaca fascicularis) (Bergin et al, 2008), a neurocysticercosis in a rhesus macaque (Macaca mulatta) (Johnston et al, 2016), and intracranial arachnoid cysts in a chimpanzee (Kaneko et al, 2013;Miyabe-Nishiwaki et al, 2014).…”

Section: Contribution To Animal Ethics and Animal Welfarementioning

confidence: 99%

The Japan Monkey Centre Primates Brain Imaging Repository of high-resolution postmortem magnetic resonance imaging: the second phase of the archive of digital records

Sakai

Hata

Shintaku

et al. 2020

Preprint

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A comparison of neuroanatomical features of the brain between humans and our evolutionary relatives, nonhuman primates, is key to understanding the human brain system and the neural basis of mental and neurological disorders. Although most comparative MRI studies of human and nonhuman primate brains have been based on brains of primates that had been used as subjects in experiments, it is essential to investigate various species of nonhuman primates in order to elucidate and interpret the diversity of neuroanatomy features among humans and nonhuman primates. To develop a research platform for this purpose, it is necessary to harmonize the scientific contributions of studies with the standards of animal ethics, animal welfare, and the conservation of brain information for long-term continuation of the field. In previous research, we first developed an open-resource repository of anatomical images obtained using 9.4-T ex vivo MRI of postmortem brain samples from 12 nonhuman primate species, and which are stored at the Japan Monkey Centre. In the present study, as a second phase, we released a collection of T2-weighted images and diffusion tensor images obtained in nine species: white-throated capuchin, Bolivian squirrel monkey, stump-tailed macaque, Tibet monkey, Sykes’ monkey, Assamese macaque, pig-tailed macaque, crested macaque, and chimpanzee. Our image repository should facilitate scientific discoveries in the field of comparative neuroscience. This repository can also promote animal ethics and animal welfare in experiments with nonhuman primate models by optimizing methods for in vivo and ex vivo MRI scanning of brains and supporting veterinary neuroradiological education. In addition, the repository is expected to contribute to conservation, preserving information about the brains of various primates, including endangered species, in a permanent digital form.

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Intracranial arachnoid cysts in a chimpanzee (Pan troglodytes)

Cited by 7 publications

References 44 publications

Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

Propofol infusions using a human target controlled infusion (TCI) pump in chimpanzees (Pan troglodytes)

A retrospective study of quadrigeminal arachnoid cysts diagnosed by Magnetic Resonance Imaging and Computed Tomography in 26 dogs

The Japan Monkey Centre Primates Brain Imaging Repository of high-resolution postmortem magnetic resonance imaging: the second phase of the archive of digital records

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