Intracranial Aneurysms in Childhood: 27-Year Single-Institution Experience

Hetts, Steven W.; Narvid, Jared; Sanai, Nader; Lawton, Michael T.; Gupta, Nalin; Fullerton, Heather J.; Dowd, Christopher F.; Higashida, Randall T.; Vv, Halbach

doi:10.3174/ajnr.a1587

Cited by 145 publications

(143 citation statements)

References 28 publications

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“…Sanai and colleagues reported that while both treatments were fairly successful, endovascular treatment is associated with a recurrence rate of 20-40 %; therefore, microsurgical treatment may be more effective in permanently obliterating aneurysms [10,11]. Approximately 21 % of children who received endovascular treatment required re-treatment of the index aneurysm [1,3]. Despite concerns for durability of endovascular treatment in pediatric UIA, we observed that there was a significant trend towards using endovascular treatment as opposed to microsurgical treatment for treating children with UIA.…”

Section: Discussionmentioning

confidence: 99%

“…The incidence of intracranial aneurysms is estimated to range from 0.5 to 4.6 % among those 18 years of age or younger [1,3,8,[10][11][12]. Aneurysms in the pediatric population differ significantly from those in the adult population.…”

Section: Introductionmentioning

confidence: 99%

“…Aneurysms in the pediatric population differ significantly from those in the adult population. These different features include predominance among boys, a higher incidence of aneurysms in the posterior circulation and the internal carotid artery bifurcation, and a higher incidence of giant aneurysms [1,3]. The three major pathophysiological mechanisms found among children that may result in intracranial aneurysms are trauma, infection, and dissection, which are less common among the aneurysms that exist within the adult population [6].…”

Section: Introductionmentioning

confidence: 99%

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Patterns of treatment and associated short-term outcomes of unruptured intracranial aneurysms in children

et al. 2014

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Background The rates and outcomes of treatments for intracranial aneurysms have not been exclusively determined within the pediatric population. We determined the rates of endovascular and microsurgical treatments for unruptured intracranial aneurysms (UIA) and associated rates of favorable outcome in patients aged <18 years. Methods We analyzed data obtained as part of the Kids' Inpatient Database between 2003 and 2009 with primary diagnosis of UIA. Patients undergoing endovascular treatment were compared to those undergoing microsurgical treatment. We determined rates of intracerebral hemorrhage, subarachnoid hemorrhage, neurological complications, and favorable outcome. Results There were 818 cases of UIA during the study period. A total of 111 patients (mean age 14±6 years, 37.6 % female) underwent microsurgical treatment, and another 200 patients (mean age 13 ± 7 years, 42.5 % female) underwent endovascular treatment. A high rate of favorable outcome was observed in patients who received either treatment (microsurgical treatment 87.7 % versus endovascular treatment 91.6 %, p=0

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Patterns of treatment and associated short-term outcomes of unruptured intracranial aneurysms in children

et al. 2014

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“…Sequelae of the tumor or its removal include visual field defects, obesity, and neurobehavioral deficits. Hypothalamic obesity in 46% of 24 cases of craniopharyngioma treated at the Phoenix Children's Hospital was refractory to current management options and accounted for increased mortality [1]. The development of obesity is influenced by premorbid obesity, genetics, and therapy received, especially radiation.…”

Section: Brain Tumors Cognitive Outcome Of Craniopharyngiomamentioning

confidence: 99%

“…An online survey of pediatric neurologists from 50 US and 11 Canadian institutions conducted in 2011 found the following common cEEG indications: altered mental status after status epilepticus (97%), altered mental status of unknown cause (88%). Median number of patients with cEEG per month per center increased from 6 per month in 2010 to 10 per month in 2011 in the US [1]. …”

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confidence: 99%