Intracranial and Spinal Tuberculosis: A Rare Entity

Rehman, Sara; Rehman, Anis; Naveed, Muhammed A; Iftikhar, Ayesha

doi:10.7759/cureus.20787

Cited by 2 publications

(1 citation statement)

References 8 publications

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“…According to a most recent meta-analysis and systematic review, patients' leg discomfort after SDS undergoes a substantial reduction that is subsequently preserved over time [ 27 - 28 ]. Investigations of people who had lumbar disc surgery produced comparable findings.…”

Section: Discussionmentioning

confidence: 99%

Postoperative Evaluation of Pain and Disability in Patients Undergoing Spinal Discectomy

Abhinav,

Jadhav,

Agrawal

et al. 2023

Cureus

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Background: A spinal discectomy surgery (SDS) is a common surgical procedure performed to treat lumbosacral radiculopathy. Aim: To evaluate postoperative patterns of pain and disability in patients undergoing spinal discectomy. Methods and materials: This investigation was a retrospective longitudinal review of prospective information gathered from 543 enrolled patients for lumbar radiculoplasty. The study participants were divided into two categories: Category 1 (SDS) comprising patients of lumbar radiculoplasty managed with SDS (n=270) and Category 2 (non-SDS) comprising patients of lumbar radiculoplasty managed with therapy other than SDS (n=273). It included study participants taking medication for pain control including opioids and non-opioids and physiotherapy for strengthening lower back muscles. At baseline, three months, 12 months, and 24 months after surgery, patient-reported information was gathered. Leg pain magnitude, back pain magnitude, and pain-related impairment were the key outcome metrics of interest. Results: The mean postoperative visual analog scale (VAS) score for leg pain at three-month follow-up was 4.3±1.2 in study participants in SDS and 8.1±1.3 in the non-SDS category. The VAS score was lower in the SDS category showing greater reduction in postoperative pain with statistically meaningful results (p<0.001). The mean postoperative VAS score at 12-month follow-up was 2.8±1.1 in study participants in SDS and 7.9±1.5 in the non-SDS category. The VAS score was lower in the SDS category showing greater reduction in postoperative pain with statistically meaningful results (p<0.001). The mean postoperative VAS score at 24-month follow-up was 1.7±1.2 in study participants in SDS and 7.1±1.1 in the non-SDS category. The VAS score was lower in the SDS category showing greater reduction in postoperative pain with statistically meaningful results (p<0.001). Conclusion: It was observed that after discectomy, patients suffering from lumbar radiculopathy have significant pain and disability recovery. According to these results, only a small percentage of individuals exhibit negative results at the level of impairment.

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Section: Discussionmentioning

confidence: 99%

Postoperative Evaluation of Pain and Disability in Patients Undergoing Spinal Discectomy

Abhinav,

Jadhav,

Agrawal

et al. 2023

Cureus

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Infections of the spinal cord and adjacent structures

2023

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ZusammenfassungEine Entzündung des Myelons und der angrenzenden Strukturen kann durch Viren, Bakterien, Pilze und Parasiten verursacht werden. Während Viren bevorzugt das Myelon und die Radizes direkt infizieren oder eine sekundäre Immunantwort triggern, neigen Bakterien, Pilze und Parasiten zur Bildung von Abszessen, Granulomen und Zysten und können wie destruierende Osteomyelitiden zu einer sekundären Myelonkompression führen. Die ätiologische Eingrenzung eines akuten/subakuten spinalen Prozesses erfolgt anhand der klinischen Präsentation, der zeitlichen Dynamik der Symptomentwicklung, des Immunstatus, der Bildgebung und mikrobieller/molekularbiologischer Untersuchungen von Liquor und Serum. Aufgrund des Tropismus einzelner Erreger zu bestimmten Faserstrukturen und Zellverbänden im Rückenmark kann in Zusammenschau mit der Klinik, der Bildgebung und der Expositionsanamnese oft bereits zeitnah eine fokussierte Abklärung und Diagnose erfolgen. In diesem Artikel wird auf wichtige Erreger einer spinalen/paraspinalen Infektion, deren geografisches Vorkommen und die klinische und bildgebende Präsentation unter besonderer Berücksichtigung der anatomisch-topografischen Lokalisation und aktueller epidemiologischer Entwicklungen eingegangen. Der Ausbruch von Poliomyelitiserkrankungen durch zirkulierende Impfstoffpolioviren (cVDPV) sei hier im Speziellen erwähnt.

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Intracranial and Spinal Tuberculosis: A Rare Entity

Cited by 2 publications

References 8 publications

Postoperative Evaluation of Pain and Disability in Patients Undergoing Spinal Discectomy

Postoperative Evaluation of Pain and Disability in Patients Undergoing Spinal Discectomy

Infections of the spinal cord and adjacent structures

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