Intracoronary ultrasound imaging: Correlation of plaque morphology with angiography, clinical syndrome and procedural results in patients undergoing coronary angioplasty

Hodgson, John McB.; Reddy, Karan G.; Suneja, Randeep; Nair, Ravi; Lesnefsky, Edward J.; Sheehan, Helen

doi:10.1016/0735-1097(93)90714-c

Cited by 334 publications

(90 citation statements)

References 36 publications

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“…Initial description of plaque morphology focused on culprit lesions in patients presenting with acute or stable coronary syndromes 93,94 . Based on these studies, a prospective intravascular ultrasound study hypothesized that certain features would be associated with the development of acute coronary syndromes during follow-up 95 .…”

Section: Plaque Composition With Ivusmentioning

confidence: 99%

Métodos por imagem da aterosclerose em estudos de progressão/regressão: marcador substituto ou janela direta para o processo patológico da aterosclerose?

Schoenhagen¹,

Tuzcu²

2008

Arq. Bras. Cardiol.

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SummaryCAD remains a major global cause of morbidity and mortality. Comprehensive drug development programs of novel pharmacological treatment strategies frequently utilize traditional mortality/morbidity endpoints studies and additional surrogate endpoints trials. This parallel approach allows an assessment of efficacy several years in advance of the availability of data from clinical endpoint trials. Several atherosclerosis imaging markers have been introduced into these drug-development strategies, including angiography, carotid ultrasound, IVUS, MRI, and CT. This review will discuss the current status of atherosclerosis imaging as an endpoint in progression/regression trials, with an emphasis on evidence-based data. In addition to a discussion of the results of individual imaging modalities, the emerging data comparing different modalities and approaches are presented.

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Section: Plaque Composition With Ivusmentioning

confidence: 99%

Métodos por imagem da aterosclerose em estudos de progressão/regressão: marcador substituto ou janela direta para o processo patológico da aterosclerose?

Schoenhagen¹,

Tuzcu²

2008

Arq. Bras. Cardiol.

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“…13) Recent studies demonstrate that these early lesions may be particularly prone to rupture. 14,15) It is conceivable that temporary thrombotic occlusion after rupture of such a lesion could cause an acute coronary syndrome in the absence of angiographic stenosis.…”

Section: Discussionmentioning

confidence: 99%

Spontaneous Intimal Dissection in a Patient with Post-Infarct Angina: Identification with Intravascular Ultrasound and Treatment with Coronary Stenting

et al. 2003

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SUMMARYA 45-year-old Turkish male patient was admitted to our hospital for an acute myocardial infarction. He had suffered two previous acute myocardial infarctions 5 and 6 years earlier. Coronary angiography performed after the previous two acute myocardial infarctions had shown normal coronary arteries and coronary vasospasm had been suspected. The patient was treated with thrombolytic therapy (rt-PA) during the last coronary event.Five days after the current admission, the patient had postinfarct angina and underwent coronary angiography, showing only a nonobstructive lesion with irregular ulcerated edges in the left anterior descending artery after the first diagonal branch. Subsequent intravascular ultrasound confirmed the presence of an atherosclerotic lesion with plaque dissection. Stenting of this lesion was performed with successful relief of on-going chest pain.Intravascular ultrasound can provide important diagnostic information in patients presenting with acute coronary syndromes in the absence of severe angiographic stenosis. Identification of plaque dissection at mildly stenotic lesions provides pathophysiologic insights that may have therapeutic implications. However, the optimal treatment for such lesions is not known. (Jpn Heart J 2003; 44: 557-564)

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“…To achieve this, quantifi able information regarding the cellular, biochemical and molecular composition of lesions needs to be obtained. Various imaging techniques, such as angioscopy (43) and intravascular ultrasonography (44,45) or more recently with optical coherence tomography, (46,47) thermography, (48,49) elastography (50,51) and magnetic resonance imaging, (52) have attempted to characterize these plaques using tissue characteristics such as fi brous cap thickness, necrotic core and the severity of the infl ammatory component in the lesions. Although promising, these technologies have shown limited clinical success.…”

Section: Imaging the Unstable Atherosclerotic Plaquementioning

confidence: 99%

Molecular Imaging of Cardiovascular Disease

Verjansr

Hofstra

2017

SAHJ

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Intracoronary ultrasound imaging: Correlation of plaque morphology with angiography, clinical syndrome and procedural results in patients undergoing coronary angioplasty

Cited by 334 publications

References 36 publications

Métodos por imagem da aterosclerose em estudos de progressão/regressão: marcador substituto ou janela direta para o processo patológico da aterosclerose?

Métodos por imagem da aterosclerose em estudos de progressão/regressão: marcador substituto ou janela direta para o processo patológico da aterosclerose?

Spontaneous Intimal Dissection in a Patient with Post-Infarct Angina: Identification with Intravascular Ultrasound and Treatment with Coronary Stenting

Molecular Imaging of Cardiovascular Disease

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